Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Facial Plast Surg Aesthet Med. 2021 Sep;23(5):389-392. doi: 10.1089/fpsam.2020.0574. Epub 2021 Mar 5.
Additional skin support is promising in scar management, especially for wounds under high tension. Options for effective skin support are limited. This study aimed to determine whether prolonged use of an adhesive wound closure (AWC) device prevents scar spread and improves final appearance. This is a split-wound randomized evaluator-blinded study of 14 patients with facial wounds under high tension. After surgical closure, one half of each wound was randomly allocated to receive either standard care or additional 3-month treatment with an AWC device. Scar width, scar scale, and side effects were evaluated 12 months after surgery. A significant difference was observed in scar width between the treated and nontreated sites at 12-month, with a mean difference of 1.024 (95% confidence interval, 0.347-1.700) mm in favor of the treated group. Scar widths in both groups increased rapidly in the first month after surgery and gradually increased until the sixth month. Scale for vascularization and relief were significantly lower in the treated sites. No significant differences were found in complications between two groups. Prolonged usage of the AWC device prevented scar spread at 12 months and improved final scar scores in vascularization and relief. Clinical Trial Registration number: ChiCTR1900027155.
额外的皮肤支撑在疤痕管理中很有前景，特别是对于高张力下的伤口。有效的皮肤支撑选择有限。本研究旨在确定延长使用粘性伤口闭合（AWC）装置是否可以防止疤痕扩散并改善最终外观。
这是一项针对面部高张力伤口的 14 名患者的分伤口随机评估者盲法研究。手术后，每个伤口的一半随机分配接受标准护理或额外的 3 个月 AWC 装置治疗。术后 12 个月评估疤痕宽度、疤痕量表和副作用。
在 12 个月时，治疗组和未治疗组的疤痕宽度存在显著差异，治疗组的平均差异为 1.024（95%置信区间，0.347-1.700）mm。两组的疤痕宽度在手术后第一个月迅速增加，并逐渐增加直到第六个月。治疗部位的血管化和缓解量表明显较低。两组之间的并发症无显著差异。
延长 AWC 装置的使用可防止 12 个月时的疤痕扩散，并改善血管化和缓解的最终疤痕评分。
ChiCTR1900027155。
