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一名儿科患者的败血症性淋菌性关节炎:罕见病例报告。

Septic gonococcal arthritis in a pediatric patient: Rare case report.

作者信息

Saini Atul, Eichenseer Clayton, Meyers Andrew, Frousiakis Petros

机构信息

Graduate Medical Education, Orthopaedic Surgery Residency Program, Community Memorial Health System, Ventura, CA, USA.

Graduate Medical Education, Orthopaedic Surgery Residency Program, Community Memorial Health System, Ventura, CA, USA.

出版信息

Int J Surg Case Rep. 2021 Mar;80:105701. doi: 10.1016/j.ijscr.2021.105701. Epub 2021 Feb 24.

Abstract

INTRODUCTION

Septic arthritis is an orthopedic emergency that requires rapid diagnosis and treatment due to the rapid destruction to cartilage. The responsible organism and etiology differs depending on patient age, especially in children. Gonococcal Arthritis in toddlers is a rare occurrence with few documented cases in the literature. An orthopedic surgeon is likely not to come across this either in training or through their careers. Consequently, its presentation and subsequent treatment algorithms leave several gray areas.

PRESENTATION OF CASE

In this case report, we present a rare and not so straightforward presentation of a toddler with septic gonococcal arthritis along with a summary of treatment considerations described in the current literature and the course of treatment for this patient. Our patient is a toddler who originally presented to the emergency department with shoulder and knee pain for several days after an unwitnessed fall. He was subsequently discharged and presented again the next day with a knee effusion and elevated inflammatory markers. An MRI showed a large joint effusion without any underlying abscess or osteomyelitis to explain his elevated inflammatory markers. A knee aspiration was subsequently preformed which eventually grew out Neisseria Gonorrhea on hospital day 3 after the patient had been on antibiotics. He was taken back for an arthroscopic irrigation and debridement for definitive treatment.

CLINICAL DISCUSSION/CONCLUSION: Disseminated gonococcal infection in toddlers is a rare occurrence without much information in the literature and should not be dismissed as a differential. We recommend a high index of suspicion with thorough work up. We also recommend surgical management of a septic joint due to DGI diagnosed via arthrocentesis (gross purulence, symptoms not improving on medical therapy, positive aspiration cultures, elevated synovial cell counts, and medically unstable patients) given the sequelae of medical management alone. The importance of interdisciplinary team collaboration that include pediatrician, infectious disease specialist, social worker, and government child safety associations is pivotal.

摘要

引言

化脓性关节炎是一种骨科急症,由于其会迅速破坏软骨,因此需要快速诊断和治疗。致病微生物和病因因患者年龄而异,在儿童中尤为如此。幼儿淋病性关节炎很少见,文献中记载的病例很少。骨科医生在培训期间或职业生涯中可能都不会遇到这种情况。因此,其临床表现和后续治疗方案存在一些不明确的地方。

病例介绍

在本病例报告中,我们展示了一名患有化脓性淋病性关节炎的幼儿罕见且不那么直接的临床表现,同时总结了当前文献中描述的治疗考虑因素以及该患者的治疗过程。我们的患者是一名幼儿,最初因无人目睹的摔倒后肩部和膝盖疼痛数天而就诊于急诊科。随后他出院了,但第二天又因膝关节积液和炎症指标升高再次就诊。磁共振成像显示有大量关节积液,但没有任何潜在脓肿或骨髓炎来解释他炎症指标升高的原因。随后进行了膝关节穿刺抽吸,最终在患者使用抗生素后的第3天培养出淋病奈瑟菌。为进行确定性治疗,他接受了关节镜冲洗和清创手术。

临床讨论/结论:幼儿播散性淋球菌感染很少见,文献中相关信息不多,不应将其排除在鉴别诊断之外。我们建议高度怀疑并进行全面检查。鉴于单纯药物治疗的后遗症,对于通过关节穿刺术诊断为播散性淋球菌感染导致的化脓性关节(有大量脓性渗出物、药物治疗症状无改善、穿刺培养阳性、滑膜细胞计数升高以及病情不稳定的患者),我们也建议进行手术治疗。包括儿科医生、传染病专家、社会工作者和政府儿童安全协会在内的多学科团队合作至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed23/7937740/0f00c2e9d936/gr1.jpg

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