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一名患有播散性淋球菌感染的儿科患者的淋球菌性骨髓炎:对抗菌治疗的启示

Gonococcal osteomyelitis in a pediatric patient with disseminated gonococcal infection: Implications for antimicrobial management.

作者信息

Liakos William, Schaffler Benjamin, Rajan Sujatha, Hagmann Stefan H F

机构信息

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Blvd, Hempstead, New York, 11549, United States.

Steven and Alexandra Cohen Children's Medical Center, Northwell Health, Division of Pediatric Infectious Diseases, 269-01 76thAve, Queens, New York, 11040, United States.

出版信息

IDCases. 2020 Jun 18;21:e00875. doi: 10.1016/j.idcr.2020.e00875. eCollection 2020.

DOI:10.1016/j.idcr.2020.e00875
PMID:32637320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7327928/
Abstract

We report a case of a female teenager with gonococcal septic arthritis of the right shoulder that also caused osteomyelitis of the humeral head. Infection with is a frequently diagnosed sexually transmitted infection in the sexually active teenage population and disseminated gonococcal infection (DGI) is the most common systemic manifestation of acute gonorrhea. DGI commonly involves acute arthritis, tenosynovitis and dermatitis with less common complications of endocarditis, hepatitis and meningitis. In contrast, osteomyelitis has only rarely been reported as a result of gonococcal infection. Clinicians need to be aware of this unusual manifestation of DGI as a prolonged duration of antimicrobial treatment may be needed to assure complete resolution of this infection.

摘要

我们报告一例女性青少年病例,其右肩发生淋菌性脓毒性关节炎,还导致了肱骨头骨髓炎。淋病奈瑟菌感染在性活跃的青少年人群中是一种经常被诊断出的性传播感染,而播散性淋菌感染(DGI)是急性淋病最常见的全身表现。DGI通常累及急性关节炎、腱鞘炎和皮炎,较少见的心内膜炎、肝炎和脑膜炎等并发症。相比之下,淋菌感染导致骨髓炎的情况仅有极少报道。临床医生需要意识到DGI的这种不寻常表现,因为可能需要延长抗菌治疗时间以确保感染完全消退。

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