Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina CH1, Ilkovičova 6, 84215 Bratislava, Slovakia.
Division of Environmental Physics, Faculty of Mathematics, Physics, and Informatics, Comenius University in Bratislava, Mlynská dolina F2, 84248 Bratislava, Slovakia.
Int J Mol Sci. 2021 Feb 24;22(5):2247. doi: 10.3390/ijms22052247.
Cold plasmas generated by various electrical discharges can affect cell physiology or induce cell damage that may often result in the loss of viability. Many cold plasma-based technologies have emerged in recent years that are aimed at manipulating the cells within various environments or tissues. These include inactivation of microorganisms for the purpose of sterilization, food processing, induction of seeds germination, but also the treatment of cells in the therapy. Mechanisms that underlie the plasma-cell interactions are, however, still poorly understood. Dissection of cellular pathways or structures affected by plasma using simple eukaryotic models is therefore desirable. Yeast is a traditional model organism with unprecedented impact on our knowledge of processes in eukaryotic cells. As such, it had been also employed in studies of plasma-cell interactions. This review focuses on the effects of cold plasma on yeast cells.
由各种电放电产生的冷等离子体可以影响细胞生理学或诱导细胞损伤，这可能经常导致细胞活力的丧失。近年来出现了许多基于冷等离子体的技术，旨在操纵各种环境或组织中的细胞。这些技术包括微生物失活以达到灭菌、食品加工、种子萌发的诱导等目的，但也包括治疗中的细胞处理。然而，等离子体与细胞相互作用的机制仍知之甚少。因此，使用简单的真核模型来剖析受等离子体影响的细胞途径或结构是可取的。酵母是一种传统的模式生物，对我们真核细胞过程的认识产生了前所未有的影响。因此，它也被用于等离子体与细胞相互作用的研究。这篇综述重点介绍了冷等离子体对酵母细胞的影响。
