Department of Biosciences, Universidade Federal de São Paulo (UNIFESP), Silva Jardim Street, 136, Vila Mathias, Santos 11015-020, SP, Brazil.
Department of Chemical, CDMF/LIEC (UFSCar) P.O. Box 676, São Carlos 13560-970, SP, Brazil.
Molecules. 2021 Feb 24;26(5):1206. doi: 10.3390/molecules26051206.
Jussara pulp ( Mart.) is rich in bioactive compounds known to be protective mediators against several diseases. In this context, nevertheless, anthocyanins, the most abundant natural pigment in jussara, are sensitive to temperature, pH, oxygen, and light conditions, leading to instability during food storage or digestion, and, thus jeopardizing the antioxidant proprieties retained by these flavonoids and limiting industrial application of the pulp. The production of nanostructures, from synthetic and natural polymers, containing natural matrices rich in bioactive compounds, has been widely studied, providing satisfactory results in the conservation and maintenance of the stability of these compounds. The current work aimed to compare uniaxial and coaxial electrospinning operation modes to produce core-shell jussara pulp nanofibers (NFs). Additionally, the parameters employed in the electrospinning processes were optimize using response surface methodology in an attempt to solve stability issues for the bioactive compounds. The best experimental conditions provided NFs with diameters ranging between 110.0 ± 47 and 121.1 ± 54 nm. Moreover, the coaxial setup improved jussara pulp NF formation, while further allowing greater integrity of NFs structures.
聚果榕（Mart.）的果肉富含生物活性化合物，已知这些化合物是预防多种疾病的保护介质。然而，在这种情况下，聚果榕中含量最丰富的天然色素——花色苷，对温度、pH 值、氧气和光照条件敏感，导致在食品储存或消化过程中不稳定，从而危及这些类黄酮保留的抗氧化特性，并限制了果肉的工业应用。从合成和天然聚合物生产含有生物活性化合物的天然基质的纳米结构的生产已经得到了广泛的研究，为这些化合物的保存和稳定性维护提供了令人满意的结果。目前的工作旨在比较单轴和同轴电纺操作模式来生产核壳结构的聚果榕果肉纳米纤维（NFs）。此外，还使用响应面法优化了电纺工艺参数，试图解决生物活性化合物的稳定性问题。最佳实验条件提供了直径在 110.0 ± 47 和 121.1 ± 54nm 之间的 NFs。此外，同轴装置改善了聚果榕果肉 NF 的形成，同时进一步保证了 NF 结构的更大完整性。
