Red Cross College of Nursing, Chung-Ang University, Seoul 06974, Korea.
Department of Nursing, Graduate School, Chung-Ang University, Seoul 06974, Korea.
Int J Environ Res Public Health. 2021 Feb 24;18(5):2237. doi: 10.3390/ijerph18052237.
Sex differences in the prognostic impact of coexisting atrial fibrillation (AF) in older patients with heart failure (HF) have not been well-studied. This study, therefore, compared sex differences in the association between AF and its 90-day adverse outcomes (hospital readmissions and emergency room (ER) visits) among older adults with HF. Of the 250 older adult patients, the prevalence rates of coexisting AF between male and female HF patients were 46.0% and 31.0%, respectively. In both male and female older patients, patients with AF have a significantly higher readmission rate (male 46.0%, and female 34.3%) than those without AF (male 6.8%, and female 12.8%). However, there are no significant differences in the association between AF and ER visits in both male and female older HF patients. The multivariate logistic analysis showed that coexisting AF significantly increased the risk of 90-day hospital readmission in both male and female older patients. In addition, older age in males and longer periods of time after an HF diagnosis in females were associated with an increased risk of hospital readmission. Consequently, prospective cohort studies are needed to identify the impact of coexisting AF on short- and long-term outcomes in older adult HF patients by sex.
在老年心力衰竭（HF）患者中，并存心房颤动（AF）对预后的影响存在性别差异，但尚未得到充分研究。因此，本研究比较了 HF 老年患者中 AF 与 90 天不良结局（住院再入院和急诊就诊）之间的相关性存在性别差异。在 250 名老年患者中，男性和女性 HF 患者中并存 AF 的患病率分别为 46.0%和 31.0%。在男性和女性老年患者中，AF 患者的再入院率（男性 46.0%，女性 34.3%）明显高于无 AF 患者（男性 6.8%，女性 12.8%）。然而，AF 与男性和女性老年 HF 患者急诊就诊之间没有显著关联。多变量逻辑分析表明，并存 AF 显著增加了男性和女性老年患者 90 天住院再入院的风险。此外，男性年龄较大和女性 HF 诊断后时间较长与再入院风险增加相关。因此，需要前瞻性队列研究来确定 AF 对老年 HF 患者短期和长期结局的影响。
