Lee Mon-Chien, Jhang Wei-Lun, Lee Chia-Chia, Kan Nai-Wen, Hsu Yi-Ju, Ho Chin-Shan, Chang Chun-Hao, Cheng Yi-Chen, Lin Jin-Seng, Huang Chi-Chang
Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 333325, Taiwan.
Culture Collection & Research Institute, Synbio Tech Incorporation, Kaohsiung 821, Taiwan.
Metabolites. 2021 Feb 25;11(3):136. doi: 10.3390/metabo11030136.
Kefir is an acidic, carbonated, and fermented dairy product produced by fermenting milk with kefir grains. The species constitutes an important part of kefir grains. In a previous animal study, kefir effectively improved exercise performance and had anti-fatigue effects. The purpose of this research was to explore the benefits of applying kefir to improve exercise performance, reduce fatigue, and improve physiological adaptability in humans. The test used a double-blind crossover design and supplementation for 28 days. Sixteen 20-30 year-old subjects were divided into two groups in a balanced order according to each individual's initial maximal oxygen uptake and were assigned to receive a placebo (equal flavor, equal calories, 20 g/day) or SYNKEFIR™ (20 g/day) every morning. After the intervention, there were 28 days of wash-out, during which time the subjects did not receive further interventions. After supplementation with SYNKEFIR™, the exercise time to exhaustion was significantly greater than that before ingestion ( = 0.0001) and higher than that in the Placebo group by 1.29-fold ( = 0.0004). In addition, compared with the Placebo group, the SYNKEFIR™ administration group had significantly lower lactate levels in the exercise and recovery ( < 0.05). However, no significant difference was observed in the changes in the gut microbiota. Although no significant changes in body composition were found, SYNKEFIR™ did not cause adverse reactions or harm to the participants' bodies. In summary, 28 days of supplementation with SYNKEFIR™ significantly improved exercise performance, reduced the production of lactic acid after exercise, and accelerated recovery while also not causing any adverse reactions.
开菲尔是一种通过用开菲尔粒发酵牛奶制成的酸性、碳酸化发酵乳制品。这些菌种是开菲尔粒的重要组成部分。在之前的一项动物研究中，开菲尔有效地提高了运动表现并具有抗疲劳作用。本研究的目的是探讨应用开菲尔来提高人类运动表现、减轻疲劳和改善生理适应性的益处。该试验采用双盲交叉设计，为期28天。16名20至30岁的受试者根据各自最初的最大摄氧量以均衡的顺序分为两组，并被指定每天早上接受安慰剂（口味相同、热量相同，20克/天）或SYNKEFIR™（20克/天）。干预后，有28天的洗脱期，在此期间受试者未接受进一步干预。补充SYNKEFIR™后，力竭运动时间显著长于摄入前（ = 0.0001），且比安慰剂组高1.29倍（ = 0.0004）。此外，与安慰剂组相比，SYNKEFIR™给药组在运动和恢复过程中的乳酸水平显著更低（ < 0.05）。然而，肠道微生物群的变化未观察到显著差异。虽然身体成分未发现显著变化，但SYNKEFIR™并未对参与者的身体造成不良反应或伤害。总之，补充SYNKEFIR™ 28天显著提高了运动表现，减少了运动后乳酸的产生，并加速了恢复，同时也未引起任何不良反应。
