Department of Medicine, Division of Geriatric, University of Verona, 37126 Verona, Italy.
Nutrients. 2021 Feb 16;13(2):635. doi: 10.3390/nu13020635.
SARC-F and Mini Sarcopenia Risk Assessment (MSRA) questionnaires have been proposed as screening tools to identify patients at risk of sarcopenia. The aim of this study is to test the use of SARC-F and MSRA, alone and combined, as a pre-screening tool for sarcopenia in geriatric inpatients.
152 subjects, 94 men and 58 women, aged 70 to 94, underwent muscle mass evaluation by dual energy X-ray absorptiometry (DXA), muscle strength evaluation by handgrip, and completed the MSRA, SARC-F and Activity of daily living (ADL) questionnaires.
66 subjects (43.4%) were classified as sarcopenic according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria. The 7-item SARC-F and MRSA and 5-item MSRA showed an area under the curve (AUC) of 0.666 (95% confidence interval (CI): 0.542-0.789), 0.730 (95% CI: 0.617-0.842) and 0.710 (95% CI: 0.593-0.827), respectively. The optimal cut-off points for sarcopenia detection were determined for each questionnaire using the Youden index method. The newly calculated cut-off points were ≤25 and ≤40 for MSRA 7- and 5-items, respectively. The ideal cut-off for the SARC-F was a score ≥3. Applying this new cut-off in our study population, sensitivity and specificity of the 7-item MSRA were 0.757 and 0.651, and 0.688 and 0.679 for the 5-item MSRA, respectively. Sensitivity and specificity of SARC-F were 0.524 and 0.765, respectively. The combined use of the 7-item SARC-F and MSRA improved the accuracy in sarcopenia diagnosis, with a specificity and sensitivity of 1.00 and 0.636.
7-item SARC-F and MSRA may be co-administered in hospital wards as an easy, feasible, first-line tool to identify sarcopenic subjects.
SARC-F 和 Mini Sarcopenia Risk Assessment（MSRA）问卷已被提议作为筛选工具，以识别有肌少症风险的患者。本研究旨在测试单独和联合使用 SARC-F 和 MSRA 作为老年住院患者肌少症的预筛查工具。
152 名受试者，94 名男性和 58 名女性，年龄 70 至 94 岁，通过双能 X 射线吸收法（DXA）评估肌肉量，通过握力评估肌肉力量，并完成 MSRA、SARC-F 和日常生活活动（ADL）问卷。
根据欧洲老年人肌少症工作组 2 （EWGSOP2）标准，66 名受试者（43.4%）被归类为肌少症。7 项 SARC-F 和 MSRA 和 5 项 MSRA 的曲线下面积（AUC）分别为 0.666（95%置信区间（CI）：0.542-0.789）、0.730（95% CI：0.617-0.842）和 0.710（95% CI：0.593-0.827）。使用 Youden 指数法确定每个问卷用于肌少症检测的最佳截断点。使用新计算的截断值，MSRA 的 7 项和 5 项的截断值分别为≤25 和≤40。SARC-F 的理想截断值为得分≥3。在我们的研究人群中应用此新截断值，7 项 MSRA 的敏感性和特异性分别为 0.757 和 0.651，5 项 MSRA 分别为 0.688 和 0.679。SARC-F 的敏感性和特异性分别为 0.524 和 0.765。7 项 SARC-F 和 MSRA 的联合使用提高了肌少症诊断的准确性，特异性和敏感性分别为 1.00 和 0.636。
7 项 SARC-F 和 MSRA 可在病房中联合使用，作为一种简便、可行的一线工具，用于识别肌少症患者。
