College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China.
Molecules. 2021 Feb 19;26(4):1090. doi: 10.3390/molecules26041090.
Cyclodextrins (CDs) are a series of cyclic oligosaccharides formed by amylose under the action of CD glucosyltransferase that is produced by Bacillus. After being modified by polymerization, substitution and grafting, high molecular weight cyclodextrin polymers (pCDs) containing multiple CD units can be obtained. pCDs retain the internal hydrophobic-external hydrophilic cavity structure characteristic of CDs, while also possessing the stability of polymer. They are a class of functional polymer materials with strong development potential and have been applied in many fields. This review introduces the research progress of pCDs, including the synthesis of pCDs and their applications in analytical separation science, materials science, and biomedicine.
环糊精(CDs)是由芽孢杆菌产生的环糊精葡萄糖基转移酶作用于淀粉而形成的一系列环状低聚糖。经过聚合、取代和接枝改性后,可得到含有多个 CD 单元的高分子量环糊精聚合物(pCDs)。pCDs 保留了 CDs 的内部疏水-外部亲水空腔结构特征,同时还具有聚合物的稳定性。它们是一类具有强大发展潜力的功能聚合物材料,已应用于许多领域。本文介绍了 pCDs 的研究进展,包括 pCDs 的合成及其在分析分离科学、材料科学和生物医药领域的应用。