EHESP, French School of Public Health, Av du Pr Léon Bernard, 35043 Rennes CEDEX, France.
Arènes UMR CNRS 6051, Université Rennes 1, 140 Bd de la Duchesse Anne, 35700 Rennes, France.
Int J Environ Res Public Health. 2021 Feb 11;18(4):1751. doi: 10.3390/ijerph18041751.
This scoping study aims to explore the relationships between urban green spaces (UGSs) and the onset, remission and recovery of cancer. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping reviews (protocol published in 2018). Eligibility criteria for papers were: (1) to be concerned with UGSs, (2) reporting effects of UGSs on cancer-related outcomes including direct or indirect measures, (3) reporting randomized controlled trials, prospective cohort studies, case studies, observational studies, non-comparative studies, (4) in English or French. The search covered primary studies in the published and unpublished (grey) literatures searching by hand and electronic databases (MEDLINE, Green File, Cumulative Index to Nursing and Allied Health Literature and ScienceDirect). Among 1703 records screened by two reviewers independently, 29 were included for qualitative synthesis. We classify the cancers concerned and the effects reported i.e., protective effect, risk or without association. The most investigated cancers are bladder, breast and lung cancer. Our study also identified contributing factors and their mediating effects between UGSs and cancer. Even though the strength of the evidence of the associations between UGSs and cancer is still weak due to the low number of studies and their design, results highlight the wide variety of possible mediating factors between the use of green spaces and cancer occurrence, remission and/or prevention. Knowledge gaps and future research perspectives should be oriented to qualitative research on protective factors with an attention to equity in UGS access and use.
本范围研究旨在探讨城市绿地(UGS)与癌症的发生、缓解和康复之间的关系。我们遵循了针对范围综述的系统评价和荟萃分析(PRISMA)扩展的偏好报告项目(2018 年发表的方案)。论文的入选标准为:(1)关注 UGS;(2)报告 UGS 对癌症相关结局的影响,包括直接或间接措施;(3)报告随机对照试验、前瞻性队列研究、病例研究、观察性研究、非对照研究;(4)以英语或法语发表。通过手工和电子数据库(MEDLINE、绿色文件、护理与健康相关文献累积索引和 ScienceDirect)搜索,对已发表和未发表(灰色)文献中的主要研究进行了搜索。在两位审稿人独立筛选的 1703 条记录中,有 29 条被纳入定性综合分析。我们对所涉及的癌症和报告的影响进行了分类,即保护作用、风险或无关联。研究最多的癌症是膀胱癌、乳腺癌和肺癌。我们的研究还确定了 UGSs 和癌症之间的一些促成因素及其介导作用。尽管由于研究数量和设计的原因,UGSs 和癌症之间关联的证据强度仍然较弱,但结果突出了在使用绿地和癌症发生、缓解和/或预防之间可能存在的多种中介因素。知识空白和未来研究的方向应侧重于关于保护因素的定性研究,并关注 UGS 获得和使用方面的公平性。