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Secular trends of Streptococcus pyogenes sepsis in Pakistan and analysis of clinical features in a hospitalized cohort.巴基斯坦化脓性链球菌败血症的长期趋势及住院队列临床特征分析
Trop Biomed. 2017 Sep 1;34(3):648-656.
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Invasive Group A streptococcal postpartum endometritis associated with multi-organ infarctions: an uncommon case presentation and literature review.侵袭性 A 组链球菌产后子宫内膜炎伴多器官梗死:一种罕见的病例表现及文献复习。
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Biphasic Outbreak of Invasive Group A Streptococcus Disease in Eldercare Facility, New Zealand.新西兰疗养院侵袭性 A 组链球菌病的双峰爆发。
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Vaccine-Induced Th1-Type Response Protects against Invasive Group A Infection in the Absence of Opsonizing Antibodies.疫苗诱导的 Th1 型反应可在没有调理抗体的情况下预防侵袭性 A 组感染。
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Clinical Description and Outcomes of Australian Children With Invasive Group A Streptococcal Disease.澳大利亚侵袭性 A 组链球菌病患儿的临床特征和结局。
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《公共卫生风险因素、预防与控制综述》

A Review of : Public Health Risk Factors, Prevention and Control.

作者信息

Avire Nelly Janira, Whiley Harriet, Ross Kirstin

机构信息

Environmental Health, College of Science and Engineering, Flinders University, Adelaide 5001, Australia.

出版信息

Pathogens. 2021 Feb 22;10(2):248. doi: 10.3390/pathogens10020248.

DOI:10.3390/pathogens10020248
PMID:33671684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7926438/
Abstract

(colloquially named "group A streptococcus" (GAS)), is a pathogen of public health significance, infecting 18.1 million people worldwide and resulting in 500,000 deaths each year. This review identified published articles on the risk factors and public health prevention and control strategies for mitigating GAS diseases. The pathogen causing GAS diseases is commonly transmitted via respiratory droplets, touching skin sores caused by GAS or through contact with contaminated material or equipment. Foodborne transmission is also possible, although there is need for further research to quantify this route of infection. It was found that GAS diseases are highly prevalent in developing countries, and among indigenous populations and low socioeconomic areas in developed countries. Children, the immunocompromised and the elderly are at the greatest risk of infections and the associated sequelae, with transmission rates being higher in schools, kindergartens, hospitals and residential care homes. This was attributed to overcrowding and the higher level of social contact in these settings. Prevention and control measures should target the improvement of living conditions, and personal and hand hygiene. Adherence to infection prevention and control practices should be emphasized in high-risk settings. Resource distribution by governments, especially in developed countries, should also be considered.

摘要

(俗称“ A组链球菌”(GAS))是一种具有公共卫生意义的病原体,全球每年有1810万人受其感染,导致50万人死亡。本综述确定了已发表的关于减轻A组链球菌疾病的危险因素以及公共卫生预防和控制策略的文章。引起A组链球菌疾病的病原体通常通过呼吸道飞沫、接触由A组链球菌引起的皮肤溃疡或通过接触受污染的材料或设备传播。食源性传播也是可能的,不过需要进一步研究来量化这种感染途径。研究发现,A组链球菌疾病在发展中国家以及发达国家的原住民和社会经济地位较低地区高度流行。儿童、免疫功能低下者和老年人感染及相关后遗症的风险最大,在学校、幼儿园、医院和养老院的传播率更高。这归因于这些场所的过度拥挤和较高的社会接触水平。预防和控制措施应着眼于改善生活条件以及个人卫生和手部卫生。在高风险场所应强调遵守感染预防和控制措施。还应考虑政府的资源分配,尤其是在发达国家。