Doctoral School of Psychology, Eotvos Lorand University, 1075 Budapest, Hungary.
Institute of Psychology, Eotvos Lorand University, 1075 Budapest, Hungary.
Int J Environ Res Public Health. 2021 Feb 14;18(4):1840. doi: 10.3390/ijerph18041840.
Although earlier research has highlighted that psychiatric disorders significantly impair patients' quality of life (QoL), few studies have examined the relationship between nonsuicidal self-injury (NSSI) and QoL. Our aim was to investigate whether QoL mediates the mental disorder-NSSI relationship, and to study the QoL ratings agreement of self and parents in a clinical population of adolescents. We involved 202 adolescents from Vadaskert Child Psychiatric Hospital and Outpatient Clinic, Budapest, aged 13-18 years. All participants completed the Deliberate Self-Harm Inventory, Inventar zur Erfassung der Lebensqualität bei Kindern und Jugendlichen, and the Mini International Neuropsychiatric Interview Kid. To map the interrelationship between the NSSI, mental disorders, and QoL dimensions, Mixed Graphical Models were estimated. Adolescents with a history of NSSI rated their QoL to be significantly lower than adolescents without NSSI. Self and parents' QoL ratings are closer in the NSSI sample than in the no-NSSI sample. Among all QoL dimensions, only family problems had a direct significant association with NSSI engagement. Our results highlight that, contrary to our hypothesis, the presence of mental disorders mediates the relationship between most QoL dimensions and the occurrence of NSSI. Our results draw attention to the potential causal effect of environmental factors (e.g., peer problems) on mental disorders that, in turn, result in NSSI. The present paper highlights the importance of network modelling in clinical research.
尽管早期的研究强调精神障碍显著损害了患者的生活质量（QoL），但很少有研究探讨非自杀性自伤（NSSI）与 QoL 之间的关系。我们的目的是调查 QoL 是否在精神障碍-NSSI 关系中起中介作用，并研究临床青少年人群中自我和父母的 QoL 评分一致性。我们共纳入了来自布达佩斯 Vadaskert 儿童精神病院和门诊部的 202 名 13-18 岁青少年。所有参与者都完成了故意自我伤害清单、儿童和青少年生活质量清单和 Mini 国际神经精神访谈儿童版。为了绘制 NSSI、精神障碍和 QoL 维度之间的相互关系图，我们估计了混合图形模型。有 NSSI 史的青少年自评 QoL 显著低于没有 NSSI 的青少年。NSSI 组中自我和父母的 QoL 评分比无 NSSI 组更接近。在所有 QoL 维度中，只有家庭问题与 NSSI 的发生有直接显著的关联。我们的结果表明，与我们的假设相反，精神障碍的存在中介了大多数 QoL 维度与 NSSI 发生之间的关系。我们的结果提请注意环境因素（例如同伴问题）对导致 NSSI 的精神障碍的潜在因果影响。本文强调了网络模型在临床研究中的重要性。
