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注意缺陷多动障碍与非自杀性自伤在青少年临床样本中的关系:共病和性别的作用。

Attention-deficit hyperactivity disorder and nonsuicidal self-injury in a clinical sample of adolescents: the role of comorbidities and gender.

机构信息

Institute of Psychology, Eötvös Loránd University, Izabella str. 46, Budapest, 1064, Hungary.

Vadaskert Child and Adolescent Psychiatry Hospital, Budapest, Hungary.

出版信息

BMC Psychiatry. 2018 Feb 6;18(1):34. doi: 10.1186/s12888-018-1620-3.

Abstract

BACKGROUND

The aim of the present study was to investigate the possible association between attention-deficit hyperactivity disorder (ADHD) and non-suicidal self-injury (NSSI) with special focus on the role of comorbidities and gender in a clinical sample of adolescents with both a dimensional and a categorical approach to psychopathology.

METHODS

Using a structured interview, the Mini International Neuropsychiatric Interview Kid and a self-rated questionnaire, the Deliberate Self-Harm Inventory, the authors examined 202 inpatient adolescents (aged: 13-18 years) in the Vadaskert Child and Adolescent Psychiatric Hospital and Outpatient Clinic, Budapest, Hungary. Descriptive statistics, Mann-Whitney U test, chi-square test and mediator model were used.

RESULTS

Fifty-two adolescents met full criteria for ADHD and a further 77 showed symptoms of ADHD at the subthreshold level. From the 52 adolescents diagnosed with ADHD, 35 (67.30%) had NSSI, of whom there were significantly more girls than boys, boys: n = 10 (28.60%), girls: n = 25 (71.40%) ((χ(1) = 10.643 p < .001 ϕ = .452). Multiple mediation analyses resulted in a moderated mediation model in which the relationship between symptoms of ADHD and the prevalence of current NSSI was fully mediated by the symptoms of comorbid conditions in both sex. Significant mediators were the symptoms of affective and psychotic disorders and suicidality in both sexes and the symptoms of alcohol abuse/dependence disorders in girls.

CONCLUSIONS

ADHD symptoms are associated with an increased risk of NSSI in adolescents, especially in the case of girls. Our findings suggest that clinicians should routinely screen for the symptoms of ADHD and comorbidity, with a special focus on the symptoms of affective disorders and alcohol abuse/dependence psychotic symptoms to prevent NSSI.

摘要

背景

本研究旨在探讨注意缺陷多动障碍(ADHD)与非自杀性自伤(NSSI)之间可能存在的关联,特别关注共病和性别在以维度和分类方法对精神病理学进行临床研究的青少年样本中的作用。

方法

研究人员使用结构化访谈、Mini 国际神经精神访谈儿童版和自我报告问卷——蓄意自我伤害清单,对匈牙利布达佩斯 Vadaskert 儿童和青少年精神病院的 202 名住院青少年(年龄:13-18 岁)进行了检查。研究人员使用了描述性统计、Mann-Whitney U 检验、卡方检验和中介模型。

结果

52 名青少年符合 ADHD 的全部诊断标准,另有 77 名青少年表现出亚临床 ADHD 症状。在被诊断为 ADHD 的 52 名青少年中,有 35 名(67.30%)有 NSSI,其中女孩明显多于男孩,男孩:n=10(28.60%),女孩:n=25(71.40%)((χ(1) = 10.643,p < 0.001,ϕ=0.452)。多项中介分析得出了一个有调节的中介模型,其中 ADHD 症状与当前 NSSI 患病率之间的关系在两性中均完全由共病症状所中介。在两性中,重要的中介变量包括情感和精神病性障碍以及自杀意念的症状,以及女孩的酒精滥用/依赖障碍症状。

结论

ADHD 症状与青少年发生 NSSI 的风险增加相关,尤其是女孩。我们的研究结果表明,临床医生应常规筛查 ADHD 症状和共病症状,特别关注情感障碍和酒精滥用/依赖症的精神病性症状,以预防 NSSI。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e227/5801900/47792f33ef49/12888_2018_1620_Fig1_HTML.jpg

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