James J E, Paull I, Cameron-Traub E, Miners J O, Lelo A, Birkett D J
School of Social Sciences, Flinders University of South Australia, Bedford Park.
J Behav Med. 1988 Feb;11(1):15-30. doi: 10.1007/BF00846166.
Increasing concern about caffeine as a drug with potential for abuse has resulted in the development of procedures for effecting reductions in caffeine consumption among heavy users. However, the reliability of reported findings may be questioned, since previous studies have relied on subject self-report as the principal measure of caffeine use. The present study employed bioanalytic methods for assessing the reliability of self-reported caffeine intake during a caffeine-fading regime. Twelve subjects, each with a history of heavy caffeine use, provided baseline, treatment, and follow-up blood samples which were assayed for caffeine and its major metabolites. General support was provided for the reliability of self-report as a measure of caffeine consumption. The general efficacy of caffeine fading was also supported, although there were indications that maintenance effects may have been over-estimated in previous studies.
人们越来越担心咖啡因作为一种有滥用潜力的药物，这导致了一些程序的开发，以减少重度使用者的咖啡因摄入量。然而，报告结果的可靠性可能会受到质疑，因为以前的研究主要依赖受试者的自我报告作为咖啡因使用的主要衡量标准。本研究采用生物分析方法来评估在咖啡因减量方案期间自我报告的咖啡因摄入量的可靠性。12名有重度咖啡因使用史的受试者提供了基线、治疗和随访血样，对其进行咖啡因及其主要代谢物的检测。自我报告作为咖啡因消费衡量标准的可靠性得到了普遍支持。咖啡因减量的总体效果也得到了支持，尽管有迹象表明，以前的研究可能高估了维持效果。
