Department of Immunology and Microbiology, Scripps Research institute, La Jolla, CA, USA.
Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.
Nat Rev Immunol. 2021 Apr;21(4):195-197. doi: 10.1038/s41577-021-00526-x.
The new vaccines against SARS-CoV-2 are novel in terms of specificity, their wide dissemination across the global population and the inclusion of newly licensed mRNA platforms. We discuss here how the approved vaccines trigger innate immunity to promote durable immunological memory and consider the future implications of protecting populations with these vaccines.
新型的 SARS-CoV-2 疫苗在特异性、在全球人群中的广泛传播以及新批准的 mRNA 平台的应用方面具有创新性。我们在这里讨论了这些批准的疫苗如何引发先天免疫以促进持久的免疫记忆，并考虑了用这些疫苗保护人群的未来意义。
