新生儿红斑狼疮表现为口腔唇溃疡：两例病例并文献复习。

Neonatal lupus erythematosus presenting as orolabial ulcerations: Two cases and a review of the literature.

机构信息

College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

School of Medicine, University of South Carolina, Columbia, SC, USA.

出版信息

Pediatr Dermatol. 2021 May;38(3):643-646. doi: 10.1111/pde.14555. Epub 2021 Mar 5.

DOI:10.1111/pde.14555

PMID:33675085

Abstract

We report two unrelated infants who presented with orolabial ulcerations as a presenting manifestation of neonatal lupus erythematosus (NLE). Subsequent positive anti-SSA/SSB titers confirmed the diagnosis. In both infants, the ulcerations were painless and spontaneously resolved. NLE should be included in the differential diagnosis of orolabial ulcerations in the newborn, especially since mothers of affected infants may be asymptomatic.

摘要

我们报告了两例非相关婴儿，他们以口唇溃疡为新生儿红斑狼疮 (NLE) 的表现。随后阳性抗 SSA/SSB 滴度证实了这一诊断。在这两个婴儿中，溃疡无痛且自行愈合。NLE 应纳入新生儿口唇溃疡的鉴别诊断，特别是因为患病婴儿的母亲可能无症状。