非影像学 axial 型脊柱关节炎患者早期颈椎结构变化的评估。
Evaluation of the early cervical structural change in patients with non-radiographic axial spondyloarthropathy.
机构信息
Department of Physical Medicine and Rehabilitation, Akdagmadeni State Hospital, Akdağmadeni, Yozgat, Turkey.
Department of Physical Medicine and Rehabilitation (Rheumatology Science), Ankara University School of Medicine, Çankaya, Ankara, Turkey.
出版信息
Rheumatol Int. 2022 Mar;42(3):495-502. doi: 10.1007/s00296-021-04807-5. Epub 2021 Mar 6.
In this double-blind, controlled, cross-sectional study, we compared structural changes in the cervical vertebrae of patients with nonradiographic axial spondyloarthropathy (nr-axSpA), patients with ankylosing spondylitis (AS), and a control group. We used the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) to determine whether the involvement of the cervical spine occurs earlier and is more severe than that of the lumbar spine in axial spondyloarthropathy (axSpA). A statistically significant difference was found in the total mSASSS between the AS and nr-axSpA groups (p = 0.038), but not in the cervical and lumbar mSASSS. Although the duration of the symptoms was shorter in the nr-axSpA group than in the AS group, no statistically significant difference was found in the cervical mSASSS between the AS and nr-axSpA groups. In both the AS and nr-axSpA groups, the cervical mSASSS values were found to be higher than the lumbar mSASSS values for the majority of the patients (82.8 and 89.5%, respectively). This may indicate that structural changes in the cervical spine occur during an early period of axSpA.
在这项双盲、对照、横断面研究中，我们比较了非放射学中轴型脊柱关节炎（nr-axSpA）、强直性脊柱炎（AS）患者和对照组患者颈椎的结构变化。我们使用改良的 Stoke 强直性脊柱炎脊柱评分（mSASSS）来确定中轴型脊柱关节炎（axSpA）中颈椎受累是否早于且重于腰椎。AS 组和 nr-axSpA 组之间的总 mSASSS 存在统计学显著差异（p=0.038），但颈椎和腰椎 mSASSS 之间没有统计学显著差异。尽管 nr-axSpA 组的症状持续时间短于 AS 组，但 AS 组和 nr-axSpA 组之间的颈椎 mSASSS 没有统计学显著差异。在 AS 组和 nr-axSpA 组中，大多数患者的颈椎 mSASSS 值均高于腰椎 mSASSS 值（分别为 82.8%和 89.5%）。这可能表明颈椎的结构变化发生在 axSpA 的早期阶段。
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