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一名糖尿病酮症酸中毒患者中表现为气管支气管肿瘤的肺毛霉菌病。

Pulmonary mucormycosis mimicking a tracheobronchial tumor in a patient with diabetic ketoacidosis.

作者信息

Elmassry Mohamed, Del Rio-Pertuz Gaspar, Karim Adnanul, Islam Ebtesam

机构信息

Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.

Department of Pulmonology and Critical Care, Texas Tech University Health Sciences Center, Lubbock, Texas.

出版信息

Proc (Bayl Univ Med Cent). 2020 Dec 16;34(2):276-278. doi: 10.1080/08998280.2020.1855618.

DOI:10.1080/08998280.2020.1855618
PMID:33678962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7901395/
Abstract

Pulmonary mucormycosis is a life-threatening infection caused by a fungus that is part of the Mucorales family. Diabetes ketoacidosis has been classically described as the main risk factor for the disease. Tracheobronchial mucormycosis is an infrequent form of pulmonary mucormycosis that presents as a tracheobronchial tumor obstructing the airway. Few cases have been reported in the literature. We present a case of pulmonary mucormycosis that presented initially as a collapsed right upper lung, mimicking a tracheobronchial tumor. Early detection and treatment are key to avoid fatal outcomes.

摘要

肺毛霉病是一种由毛霉目真菌引起的危及生命的感染。糖尿病酮症酸中毒一直被经典地描述为该疾病的主要危险因素。气管支气管毛霉病是肺毛霉病的一种罕见形式,表现为阻塞气道的气管支气管肿瘤。文献中报道的病例很少。我们报告一例肺毛霉病,最初表现为右上肺萎陷,酷似气管支气管肿瘤。早期检测和治疗是避免致命后果的关键。

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Proc (Bayl Univ Med Cent). 2020 Dec 16;34(2):276-278. doi: 10.1080/08998280.2020.1855618.
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本文引用的文献

1
Pulmonary mucormycosis with extensive bronchial necrosis and bronchomediastinal fistula: A case report and review.伴有广泛支气管坏死和支气管纵隔瘘的肺毛霉菌病:一例报告及文献复习
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2
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Lancet Infect Dis. 2019 Dec;19(12):e405-e421. doi: 10.1016/S1473-3099(19)30312-3. Epub 2019 Nov 5.
3
Pulmonary Mucormycosis in a Patient With Uncontrolled Diabetes.一名糖尿病控制不佳患者的肺毛霉菌病
Fed Pract. 2018 Jan;35(1):32-36.
4
A prospective multicenter study on mucormycosis in India: Epidemiology, diagnosis, and treatment.印度毛霉菌病的前瞻性多中心研究:流行病学、诊断与治疗
Med Mycol. 2019 Jun 1;57(4):395-402. doi: 10.1093/mmy/myy060.
5
Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management.难治性支气管血管性胸膜肺毛霉病:病例报告及管理难点
Lung India. 2018 Jan-Feb;35(1):70-72. doi: 10.4103/lungindia.lungindia_535_16.
6
Report of 12 cases with tracheobronchial mucormycosis and a review.12例气管支气管毛霉菌病报告及文献复习
Clin Respir J. 2018 Apr;12(4):1651-1660. doi: 10.1111/crj.12724. Epub 2018 Feb 19.
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Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis.伊曲康唑治疗毛霉病:一项单臂开放标签试验和病例对照分析。
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Mucormycosis masquerading as an endobronchial tumor.伪装成支气管内肿瘤的毛霉菌病。
Lung India. 2014 Jul;31(3):308-10. doi: 10.4103/0970-2113.135798.
9
Mucormycosis treated with posaconazole: review of 96 case reports.泊沙康唑治疗毛霉病:96 例病例报告综述。
Crit Rev Microbiol. 2013 Aug;39(3):310-24. doi: 10.3109/1040841X.2012.711741. Epub 2012 Aug 24.
10
Epidemiology and outcome of zygomycosis: a review of 929 reported cases.毛霉菌病的流行病学与转归:929例报告病例的综述
Clin Infect Dis. 2005 Sep 1;41(5):634-53. doi: 10.1086/432579. Epub 2005 Jul 29.