Seifert S, Wiley J, Kirkham J, Lena S, Schiers K
Department of Pulmonary Medicine, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
Department of Pulmonary and Critical Care Medicine, Jefferson Health New Jersey, Sewell, NJ, USA.
Respir Med Case Rep. 2020 May 6;30:101082. doi: 10.1016/j.rmcr.2020.101082. eCollection 2020.
Mucormycosis is a life-threatening infection caused by fungi in the Mucorales species. It most often affects immunocompromised hosts, including diabetics patients. It can affect a variety of organ systems with pulmonary manifestations being the second most common. In severe cases, significant bronchial necrosis and angioinvasion can be seen. Due to its rarity, such extensive cases are not often reported in literature. We present a case of a 32-year-old man who presented with severe bronchial necrosis, including bronchomediastinal fistula, due to Rhizopus. Despite prompt treatment, he developed massive hemoptysis from invasion of the pulmonary vasculature and died. We also provide a brief review of mucormycosis.
毛霉病是一种由毛霉目真菌引起的危及生命的感染。它最常影响免疫功能低下的宿主，包括糖尿病患者。它可累及多种器官系统，肺部表现是第二常见的。在严重病例中，可见明显的支气管坏死和血管侵袭。由于其罕见性，此类广泛病例在文献中并不常被报道。我们报告一例32岁男性患者，因根霉感染出现严重的支气管坏死，包括支气管纵隔瘘。尽管及时治疗，但由于肺血管受侵，他出现大量咯血并死亡。我们还对毛霉病进行了简要综述。
