Faiz Samira, Qureshi Farhan Muhammad, Hussain Amreen Wasif, Nigah-E-Mumtaz Seema
Dr. Samira Faiz, MPH. Senior Lecturer, Department of Community Health Sciences, Karachi Institute of Medical Sciences, Malir Cantt, Karachi, Pakistan.
Dr. Farhan Muhammad Qureshi, MS - Public Health & Health Promotion Assistant Professor, Department of Community Health Sciences, Karachi Institute of Medical Sciences, Malir Cantt, Karachi, Pakistan.
Pak J Med Sci. 2021 Mar-Apr;37(2):477-482. doi: 10.12669/pjms.37.2.3426.
Subjective memory complaints (SMCs) are suggested to predict dementia at a very early stage. However, association of SMCs with known risk factors of dementia namely diabetes mellitus Type-2 diabetes and hypertension (HTN) remain unexplored which is the main aim of this study. The objective of the study was to investigate the association of SMC with diabetes mellitus type 2 (DM2) and hypertension (HTN).
The associations of diabetes and hypertension, with SMCs has been tested in 500 participants from a tertiary care hospital of Karachi during 2017. Diagnosed cases of diabetes and hypertension were included through convenient sampling. Healthy attendants of patients were interviewed for the reference group. SMCs were assessed through a 14-item SMC questionnaire.
Sample included 114 patients with only diabetes and hypertension each, 103 with both diabetes and hypertension and 169 healthy participants. Compared to healthy adults, persons with diabetes and hypertension had higher SMCs (difference, 0.88, 95% CI: 0.22, 1.54) (difference, 1.06, 95% CI: 0.40, 1.71) respectively, in fully adjusted models.
Compared to healthy adults of working age-group, persons with diabetes and hypertension were more likely to have SMCs. Assessment and early detection of SMCs in persons with diabetes and hypertension might be informative to provide a window for effective interventions to maintain cognitive health.
主观记忆障碍（SMCs）被认为可在极早期预测痴呆。然而，SMCs与已知痴呆风险因素即2型糖尿病和高血压（HTN）之间的关联尚未得到探索，这是本研究的主要目的。本研究的目的是调查SMCs与2型糖尿病（DM2）和高血压（HTN）之间的关联。
2017年期间，在卡拉奇一家三级护理医院的500名参与者中测试了糖尿病和高血压与SMCs的关联。通过方便抽样纳入已确诊的糖尿病和高血压病例。对患者的健康陪护人员进行访谈作为参照组。通过一份包含14个条目的SMC问卷评估SMCs。
样本包括114名仅患有糖尿病的患者、114名仅患有高血压的患者、103名同时患有糖尿病和高血压的患者以及169名健康参与者。在完全调整模型中，与健康成年人相比，患有糖尿病和高血压的人分别有更高的SMCs（差异为0.88，95%可信区间：0.22，1.54）（差异为1.06，95%可信区间：0.40，1.71）。
与工作年龄组的健康成年人相比，患有糖尿病和高血压的人更有可能出现SMCs。对糖尿病和高血压患者的SMCs进行评估和早期检测可能有助于提供一个窗口，以便进行有效的干预以维持认知健康。
