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疱疹样皮炎中循环免疫球蛋白A抗基底膜带抗体

Circulating IgA anti-basement membrane zone antibodies in dermatitis herpetiformis.

作者信息

Yaoita H, Katz S I

出版信息

J Invest Dermatol. 1977 Dec;69(6):558-60. doi: 10.1111/1523-1747.ep12688382.

DOI:10.1111/1523-1747.ep12688382
PMID:336800
Abstract

Criculating anti-basement membrane zone antibodies of the IgA class were detected in the sera of 2 or 6 dermatitis herpetiformis (DH) patients who had linear in-vivo-bound IgA deposits and in 1 of 42 DH patients who had granular vivo-bound IgA deposits. In the former 2 patients the circulating antibodies were localized ultrastructurally to the identical site where the in vivo-bound antibodies were localized and were bound by antigens in either the lamina lucida or the subbasal lamina anchoring fibril area of the basement membrane zone of normal human skin.

摘要

在2例或6例有线性体内结合IgA沉积的疱疹样皮炎(DH)患者的血清中,以及42例有颗粒状体内结合IgA沉积的DH患者中的1例血清中,检测到IgA类循环抗基底膜带抗体。在前2例患者中,循环抗体在超微结构上定位于与体内结合抗体相同的部位,并被正常人皮肤基底膜带透明层或基底膜下锚原纤维区域的抗原所结合。

相似文献

1
Circulating IgA anti-basement membrane zone antibodies in dermatitis herpetiformis.疱疹样皮炎中循环免疫球蛋白A抗基底膜带抗体
J Invest Dermatol. 1977 Dec;69(6):558-60. doi: 10.1111/1523-1747.ep12688382.
2
Dermatitis herpetiformis with linear IgA deposition: ultrastructural localization of in vivo bound IgA.线状IgA沉积的疱疹样皮炎:体内结合IgA的超微结构定位
Acta Derm Venereol. 1982;62(5):401-5.
3
Circulating IgA anti-basement membrane antibodies in linear dermatitis herpetiformis (Duhring): immunofluorescence and immunoelectronmicroscopic studies.疱疹样皮炎(杜林病)中的循环免疫球蛋白A抗基底膜抗体:免疫荧光和免疫电子显微镜研究
J Invest Dermatol. 1977 Nov;69(5):490-3. doi: 10.1111/1523-1747.ep12511758.
4
The ultrastructural localization of IgA in skin of a patient with mixed form of dermatitis herpetiformis and bullous pemphigoid.疱疹样皮炎和大疱性类天疱疮混合型患者皮肤中IgA的超微结构定位
J Invest Dermatol. 1978 Feb;70(2):76-9. doi: 10.1111/1523-1747.ep12541207.
5
Chronic bullous disease of childhood and linear IgA disease of adults are IgA1-mediated diseases.儿童慢性大疱性疾病和成人线状IgA疾病是IgA1介导的疾病。
Br J Dermatol. 1994 Aug;131(2):201-4. doi: 10.1111/j.1365-2133.1994.tb08491.x.
6
IgA-binding structures in dermatitis herpetiformis skin are independent of elastic-microfibrillar bundles.疱疹样皮炎皮肤中的IgA结合结构独立于弹性微原纤维束。
J Invest Dermatol. 1991 Jan;96(1):88-92. doi: 10.1111/1523-1747.ep12515903.
7
IgA deposits in the oral mucosa of patients with dermatitis herpetiformis and linear IgA disease.疱疹样皮炎和线状IgA疾病患者口腔黏膜中的IgA沉积。
Scand J Dent Res. 1984 Jun;92(3):230-4. doi: 10.1111/j.1600-0722.1984.tb00884.x.
8
Immunoelectronmicroscopic localization of IgA in skin of patients with dermatitis herpetiformis.疱疹样皮炎患者皮肤中IgA的免疫电子显微镜定位
J Invest Dermatol. 1976 Oct;67(4):502-6. doi: 10.1111/1523-1747.ep12664534.
9
IgA class antibodies in dermatitis herpetiformis: reaction with tissue antigens.疱疹样皮炎中的IgA类抗体:与组织抗原的反应
J Invest Dermatol. 1989 Aug;93(2):253-8. doi: 10.1111/1523-1747.ep12277583.
10
Immunoelectron microscopic findings in oral mucosa of patients with dermatitis herpetiformis and linear IgA disease.疱疹样皮炎和线状IgA疾病患者口腔黏膜的免疫电子显微镜检查结果
Scand J Dent Res. 1985 Jun;93(3):243-8. doi: 10.1111/j.1600-0722.1985.tb01952.x.

引用本文的文献

1
Linear Immunoglobulin a Bullous Dermatosis in Children.儿童线状免疫球蛋白A大疱性皮肤病
Front Pediatr. 2022 Jul 8;10:937528. doi: 10.3389/fped.2022.937528. eCollection 2022.
2
Dermatitis herpetiformis.疱疹样皮炎
Springer Semin Immunopathol. 1981 Jun;4(1):33-43. doi: 10.1007/BF01891883.
3
Linear IgA dapsone responsive bullous dermatosis.线性IgA大疱性皮肤病伴氨苯砜反应
J R Soc Med. 1980 May;73(5):371-3. doi: 10.1177/014107688007300515.
4
Immunoelectron microscopic studies in IgA linear dermatosis.IgA 线状皮肤病的免疫电子显微镜研究。
Arch Dermatol Res. 1979 Jul 30;265(3):289-98. doi: 10.1007/BF00412386.