Department of Sport Rehabilitation, Shanghai University of Sport, 399 Changhai RD, Shanghai 200438, China.
Luoyang Orthopedic Hospital of Henan Province, 82 Qimingnan RD, Luoyang 471000, China.
Pain Res Manag. 2021 Feb 17;2021:6655211. doi: 10.1155/2021/6655211. eCollection 2021.
To provide a comprehensive review on the global scientific research status of comorbid pain and inflammation from 1981 to 2019 and capture its subsequent development trends. . The primary database chosen to collect publications on comorbid pain and inflammation research from 1981 to 2019 was the Web of Science (WOS). Core of the search strategy was the key word "pain" and the key word "inflammation" in the medical subject headings' major field. Study Selection. All articles retrieved were included in the bibliometric analysis. . We used CiteSpace to analyze publication outputs, subject categories, distribution by country/institution/journal, and other types of information. Then, knowledge base, hot issues, and future development directions were explained. . A total of 2887 papers met the inclusion criteria in our research. Linear regression analysis results showed that the publications of studies of comorbid pain and inflammation significantly increased ( < 0.001) and have grown about 192 times in 40 years. The countries with the most outputs were the USA (886 publications), China (375 publications), and England (236 publications). Besides, Harvard University was the most prolific institution with 730 publications and 6646 citations. In accordance with the subject categories of WOS, neurosciences (31.832%), pharmacology/pharmacy (18.427%), and clinical neurology (15.206%) were the main research areas of these 2887 papers.
The current study reveals that research on comorbid pain and inflammation has gradually become more extensive worldwide since 1981, and neuropathic pain was the most popular study type. Most of our research output in this field came from countries in Europe and North America, although some Asian countries showed promising performance.
全面回顾 1981 年至 2019 年全球关于合并疼痛和炎症的科学研究现状，并捕捉其后续发展趋势。方法：选择 Web of Science (WOS) 作为收集 1981 年至 2019 年合并疼痛和炎症研究出版物的主要数据库。搜索策略的核心是主题字段中的关键词“疼痛”和关键词“炎症”。研究选择：所有检索到的文章均包含在文献计量分析中。结果：我们使用 CiteSpace 分析了出版物产出、主题类别、按国家/机构/期刊的分布以及其他类型的信息。然后，解释了知识库、热点问题和未来的发展方向。共纳入 2887 篇符合研究标准的文章。线性回归分析结果表明，合并疼痛和炎症研究的出版物显著增加（<0.001），40 年来增长了约 192 倍。产出最多的国家是美国（886 篇）、中国（375 篇）和英国（236 篇）。此外，哈佛大学是发表论文数量最多的机构，有 730 篇论文和 6646 次引用。根据 WOS 的主题类别，神经科学（31.832%）、药理学/药学（18.427%）和临床神经病学（15.206%）是这 2887 篇论文的主要研究领域。结论：本研究表明，自 1981 年以来，全球范围内关于合并疼痛和炎症的研究逐渐变得更加广泛，神经病理性疼痛是最受欢迎的研究类型。虽然一些亚洲国家表现出了良好的发展态势，但该领域的研究成果主要来自欧洲和北美国家。
