Zhang Minchen, Zhou Rong, Wu Jun, Chen Lulu, Ren Zijian, Gao Weicheng
Department of Plastic and Cosmetic Surgery, The Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, Jiangsu, China.
Plast Reconstr Surg Glob Open. 2021 Feb 18;9(2):e3437. doi: 10.1097/GOX.0000000000003437. eCollection 2021 Feb.
The purpose of this article is to clarify the character of Müller's muscle in Chinese specimens.
Ten upper eyelids of 10 formalin-fixed Chinese cadavers (9 elderly people, from 68 to 86 years of age; 1 male child, 10 years old) were examined. Full-thickness sagittal sections of the central part of the upper eyelids were microscopically examined using hematoxylin-eosin, Masson trichrome, and anti-smooth muscle actin antibodies staining.
In 9 elderly specimens, Müller's muscle inserted onto tarsus via fibers, and the smooth muscle components decreased gradually and even faded away from the originated inferior branch of levator palpebrae superioris muscle to the upper margin of tarsus, although, in 1 child specimen, Müller's muscle inserted directly onto tarsus rather than connective fibrous structure, and smooth muscle components did not decrease obviously. Both in elderly and young specimens, the aponeurotic structure that originated from Müller's muscle extended to the tarsal plate.
This study suggests that Müller's muscle inserts onto the tarsus via fibrous tissue or smooth muscle, and also indicates that the smooth components of Müller's muscle may decrease gradually in elderly people.
本文旨在阐明中国标本中米勒肌的特征。
检查了10具用福尔马林固定的中国尸体的10只上睑（9名老年人，年龄68至86岁；1名男童，10岁）。对上睑中央部分的全层矢状切片进行苏木精-伊红、马松三色染色和抗平滑肌肌动蛋白抗体染色后进行显微镜检查。
在9例老年标本中，米勒肌通过纤维插入睑板，平滑肌成分从提上睑肌的起始下支至睑板上缘逐渐减少甚至消失，不过，在1例儿童标本中，米勒肌直接插入睑板而非结缔纤维结构，且平滑肌成分无明显减少。在老年和年轻标本中，源自米勒肌的腱膜结构均延伸至睑板。
本研究表明，米勒肌通过纤维组织或平滑肌插入睑板，还表明米勒肌的平滑肌成分在老年人中可能会逐渐减少。
