Diamond M P, Baxter J W, Peerman C G, Burnett L S
Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee.
Obstet Gynecol. 1988 Jun;71(6 Pt 1):858-60.
During childhood and adolescence, the rate of malignancy in ovarian enlargement is reported to be high-approximately 35% in many large series from tertiary centers. To assess whether this represents an overestimation because of the referral patterns of these institutions, a retrospective review was conducted at five hospitals in Nashville, Tennessee. In females 21 years of age and under, borderline or malignant ovarian neoplasms were identified in only eight (5.8%) of 137 individuals with ovarian enlargement and eight (9.8%) of 82 females with ovarian neoplasms. All six malignant neoplasms were of germ-cell origin. The borderline neoplasms were of epithelial origin, and occurred in females in their late teens. We conclude that the frequency with which ovarian enlargement represents malignancy in this age group appears to be much smaller than previously suggested. Nevertheless, because of the potential for malignant ovarian neoplasia in young females, the presence of an abdominal-pelvic mass requires prompt and thorough attention.
在儿童期和青春期，据报道卵巢肿大时恶性肿瘤的发生率很高——在许多来自三级医疗中心的大型研究系列中约为35%。为了评估这是否由于这些机构的转诊模式而被高估，在田纳西州纳什维尔的五家医院进行了一项回顾性研究。在21岁及以下的女性中，137例卵巢肿大患者中仅有8例（5.8%）被诊断为交界性或恶性卵巢肿瘤，82例卵巢肿瘤女性中有8例（9.8%）被诊断为此类疾病。所有6例恶性肿瘤均起源于生殖细胞。交界性肿瘤起源于上皮细胞，发生在接近20岁的女性中。我们得出结论，在这个年龄组中，卵巢肿大代表恶性肿瘤的频率似乎比之前认为的要小得多。然而，由于年轻女性存在卵巢恶性肿瘤的可能性，腹盆腔肿块的出现需要及时和全面的关注。
