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“恶性淋巴上皮病变”(腮腺未分化导管癌)。三例病例报告及文献综述

'Malignant lymphoepithelial lesions' (undifferentiated ductal carcinomas of the parotid gland). Three case reports and review of the literature.

作者信息

Ferlito A, Donati L F

出版信息

J Laryngol Otol. 1977 Oct;91(10):869-83. doi: 10.1017/s0022215100084498.

DOI:10.1017/s0022215100084498
PMID:336820
Abstract

Three cases of the so-cassed malignant lymphoepithelial lesion occurring in women are described. The authors, however, prefer to label the lesion 'undifferentiated carcinoma of the parotid'. From an accurate review of the world literature it appears that 23 cases of such lesion have been reported, 22 arising in the parotid and 1 in the submandibular gland. The malignant lymphoepithelial lesion has been mainly encountered in Eskimos and the three cases of the present report are the first to have been evidenced in Europe. The malignant lymphoepithelial lesion is discussed from the taxonomic, nosologic, pathogenetic, diagnostic and therapeutic points of view. The lesion does not seem to be of an autoimmune nature, unlike the benign lymphoepithelial lesion which is generally regarded as an autoimmune disease.

摘要

本文描述了3例发生于女性的所谓恶性淋巴上皮病变。然而,作者更倾向于将该病变标记为“腮腺未分化癌”。通过对世界文献的精确回顾,发现已报道了23例此类病变,其中22例发生于腮腺,1例发生于下颌下腺。恶性淋巴上皮病变主要见于爱斯基摩人,本报告中的3例是欧洲首次证实的病例。本文从分类学、疾病分类学、发病机制、诊断和治疗等角度对恶性淋巴上皮病变进行了讨论。与通常被视为自身免疫性疾病的良性淋巴上皮病变不同,该病变似乎不具有自身免疫性质。

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引用本文的文献

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Cancers (Basel). 2020 Aug 27;12(9):2431. doi: 10.3390/cancers12092431.
2
Primary parotid lymphoepithelial carcinoma: A case report and literature review of a rare pathological entity.原发性腮腺淋巴上皮癌:一例罕见病理实体的病例报告及文献复习
Int J Surg Case Rep. 2020;72:610-614. doi: 10.1016/j.ijscr.2020.06.035. Epub 2020 Jun 12.
3
Lymphoepithelial-like carcinoma of the parotid gland: a case report and a brief review of the western literature.
腮腺淋巴上皮样癌:一例报告及对西方文献的简要回顾。
Diagn Pathol. 2013 Jul 15;8:115. doi: 10.1186/1746-1596-8-115.
4
[Undifferentiated salivary gland carcinomas].
Pathologe. 2004 Feb;25(1):56-62. doi: 10.1007/s00292-003-0674-1.
5
Malignant epithelial tumours associated with autoimmune sialadenitis.与自身免疫性涎腺炎相关的恶性上皮性肿瘤。
J Clin Pathol. 1986 May;39(5):497-502. doi: 10.1136/jcp.39.5.497.