• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

机械循环支持在急性心肌梗死和心源性休克中的应用：随机对照试验的挑战和重要性。

Mechanical circulatory support in acute myocardial infarction and cardiogenic shock: Challenges and importance of randomized control trials.

机构信息

Cardiology, Henry Ford Health System, Detroit, Michigan, USA.

Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

出版信息

Catheter Cardiovasc Interv. 2021 Dec 1;98(7):1264-1274. doi: 10.1002/ccd.29593. Epub 2021 Mar 7.

DOI:10.1002/ccd.29593
PMID:33682260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8421448/
Abstract

BACKGROUND

Acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) is associated with significant morbidity and mortality.

METHODS

We provide an overview of previously conducted studies on the use of mechanical circulatory support (MCS) devices in the treatment of AMI-CS and difficulties which may be encountered in conducting such trials in the United States.

RESULTS

Well powered randomized control trials are difficult to conduct in a critically ill patient population due to physician preferences, perceived lack of equipoise and challenges obtaining informed consent.

CONCLUSIONS

With growth in utilization of MCS devices in patients with AMI-CS, efforts to perform well-powered, randomized control trials must be undertaken.

摘要

背景

急性心肌梗死（AMI）并发心源性休克（CS）与较高的发病率和死亡率相关。

方法

我们对机械循环支持（MCS）设备在治疗 AMI-CS 中的应用进行了综述，并探讨了在美国开展此类试验可能遇到的困难。

结果

由于医生的偏好、缺乏平衡感以及获得知情同意的挑战，在病情危急的患者群体中开展大型随机对照试验具有一定难度。

结论

随着 AMI-CS 患者中 MCS 设备的使用不断增加，必须努力开展大规模、随机对照试验。

相似文献

1
Mechanical circulatory support in acute myocardial infarction and cardiogenic shock: Challenges and importance of randomized control trials.机械循环支持在急性心肌梗死和心源性休克中的应用：随机对照试验的挑战和重要性。
Catheter Cardiovasc Interv. 2021 Dec 1;98(7):1264-1274. doi: 10.1002/ccd.29593. Epub 2021 Mar 7.
2
Safety and utility of mechanical circulatory support in patients with acute myocardial infarction complicated by cardiogenic shock: A systematic review and meta-analysis.急性心肌梗死合并心源性休克患者机械循环支持的安全性与实用性：一项系统评价与荟萃分析。
Cardiovasc Revasc Med. 2025 Jan;70:23-33. doi: 10.1016/j.carrev.2024.06.016. Epub 2024 Jun 21.
3
A Systematic Review and Meta-Analysis of the Efficacy and Safety of Combined Mechanical Circulatory Support in Acute Myocardial Infarction Related Cardiogenic Shock.急性心肌梗死相关心源性休克中联合机械循环支持疗效与安全性的系统评价和荟萃分析
Catheter Cardiovasc Interv. 2025 Feb;105(3):650-661. doi: 10.1002/ccd.31369. Epub 2024 Dec 24.
4
Comparison of temporary mechanical circulatory support devices for patients with cardiogenic shock after acute myocardial infarction: A network meta-analysis of randomized controlled trials.急性心肌梗死后心源性休克患者临时机械循环支持装置的比较：一项随机对照试验的网状Meta分析
Int J Cardiol. 2025 Mar 15;423:132997. doi: 10.1016/j.ijcard.2025.132997. Epub 2025 Jan 25.
5
Trends in mechanical circulatory support use and hospital mortality among patients with acute myocardial infarction and non-infarction related cardiogenic shock in the United States.美国急性心肌梗死合并非梗死相关心原性休克患者应用机械循环支持治疗的趋势和院内死亡率。
Clin Res Cardiol. 2018 Apr;107(4):287-303. doi: 10.1007/s00392-017-1182-2. Epub 2017 Nov 13.
6
Mechanical circulatory support versus vasopressors alone in patients with acute myocardial infarction and cardiogenic shock undergoing percutaneous coronary intervention.机械循环支持与单独使用血管加压素在接受经皮冠状动脉介入治疗的急性心肌梗死合并心原性休克患者中的比较。
Catheter Cardiovasc Interv. 2024 Jan;103(1):30-41. doi: 10.1002/ccd.30913. Epub 2023 Nov 23.
7
Mechanical circulatory support with the Impella® LP5.0 pump and an intra-aortic balloon pump for cardiogenic shock in acute myocardial infarction: The IMPELLA-STIC randomized study.急性心肌梗死后心源性休克应用 Impella® LP5.0 泵和主动脉内球囊反搏进行机械循环支持：IMPELLA-STIC 随机研究。
Arch Cardiovasc Dis. 2020 Apr;113(4):237-243. doi: 10.1016/j.acvd.2019.10.005. Epub 2019 Nov 15.
8
Impella Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock.经皮 Impella 辅助治疗伴心原性休克的急性心肌梗死。
Circulation. 2019 Mar 5;139(10):1249-1258. doi: 10.1161/CIRCULATIONAHA.118.036614.
9
Mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock.机械循环支持在急性心肌梗死并发心源性休克中的应用。
Rev Cardiovasc Med. 2022 Feb 21;23(2):71. doi: 10.31083/j.rcm2302071.
10
Outcomes of mechanical circulatory support for acute myocardial infarction complicated by cardiogenic shock.机械循环支持治疗急性心肌梗死合并心原性休克的疗效。
Catheter Cardiovasc Interv. 2022 Feb;99(3):658-663. doi: 10.1002/ccd.29834. Epub 2021 Jun 22.

引用本文的文献

1
Managing the acute cardiac functional crisis: a comprehensive review of cardiogenic shock management strategies.急性心功能危机的管理：心源性休克管理策略的全面综述
Eur Heart J Suppl. 2025 Feb 4;27(Suppl 4):iv4-iv11. doi: 10.1093/eurheartjsupp/suae125. eCollection 2025 Apr.
2
Current Landscape of Temporary Percutaneous Mechanical Circulatory Support Technology.临时经皮机械循环支持技术的现状
US Cardiol. 2021 Nov 2;15:e21. doi: 10.15420/usc.2021.15. eCollection 2021.
3
Prolonged Impella 5.0/5.5 support within different pathways of care for cardiogenic shock: the experience of a referral center.

本文引用的文献

1
Veno-arterial extracorporeal membrane oxygenation (ECMO) in patients with cardiogenic shock: rationale and design of the randomised, multicentre, open-label EURO SHOCK trial.静脉-动脉体外膜肺氧合（ECMO）在心源性休克患者中的应用：随机、多中心、开放标签 EURO SHOCK 试验的原理和设计。
EuroIntervention. 2021 Feb 5;16(15):e1227-e1236. doi: 10.4244/EIJ-D-20-01076.
2
Extracorporeal Membrane Oxygenation Use in Acute Myocardial Infarction in the United States, 2000 to 2014.美国 2000 年至 2014 年体外膜肺氧合在急性心肌梗死中的应用。
Circ Heart Fail. 2019 Dec;12(12):e005929. doi: 10.1161/CIRCHEARTFAILURE.119.005929. Epub 2019 Dec 12.
3
在不同的心源性休克治疗途径中延长使用Impella 5.0/5.5支持：一家转诊中心的经验
Front Cardiovasc Med. 2024 Jul 2;11:1379199. doi: 10.3389/fcvm.2024.1379199. eCollection 2024.
4
Contemporary approach to cardiogenic shock care: a state-of-the-art review.心源性休克治疗的当代方法：一项最新综述。
Front Cardiovasc Med. 2024 Mar 13;11:1354158. doi: 10.3389/fcvm.2024.1354158. eCollection 2024.
5
Cardiogenic Shock in Older Adults: A Focus on Age-Associated Risks and Approach to Management: A Scientific Statement From the American Heart Association.老年人心源性休克：关注与年龄相关的风险和管理方法：美国心脏协会的科学声明。
Circulation. 2024 Apr 2;149(14):e1051-e1065. doi: 10.1161/CIR.0000000000001214. Epub 2024 Feb 26.
6
Early Utilization of Mechanical Circulatory Support in Acute Myocardial Infarction Complicated by Cardiogenic Shock: The National Cardiogenic Shock Initiative.急性心肌梗死并发心源性休克患者机械循环支持的早期应用：国家心源性休克倡议。
J Am Heart Assoc. 2023 Dec 5;12(23):e031401. doi: 10.1161/JAHA.123.031401. Epub 2023 Nov 28.
7
One-Year Survival for Developing Acute Kidney Injury in Adult Patients with AMI Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation.接受静脉-动脉体外膜肺氧合治疗的急性心肌梗死心源性休克成年患者发生急性肾损伤的一年生存率
Int J Gen Med. 2023 Oct 5;16:4537-4548. doi: 10.2147/IJGM.S427999. eCollection 2023.
8
Real-World Data on the Intravascular Microaxial Left Ventricular Flow Pump (Impella) in High-Risk Patients.高危患者使用血管内微轴左心室血流泵（Impella）的真实世界数据。
Korean Circ J. 2021 Jun;51(6):487-494. doi: 10.4070/kcj.2021.0102.
Ten-year trends, predictors and outcomes of mechanical circulatory support in percutaneous coronary intervention for acute myocardial infarction with cardiogenic shock.
经皮冠状动脉介入治疗伴心原性休克的急性心肌梗死后十年机械循环支持的趋势、预测因素和结局。
EuroIntervention. 2021 Feb 5;16(15):e1254-e1261. doi: 10.4244/EIJ-D-19-00226.
4
The Evolving Landscape of Impella Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention With Mechanical Circulatory Support.美国经皮冠状动脉介入治疗中机械循环支持患者中 Impella 使用的演变情况。
Circulation. 2020 Jan 28;141(4):273-284. doi: 10.1161/CIRCULATIONAHA.119.044007. Epub 2019 Nov 17.
5
Clinical Practice Patterns in Temporary Mechanical Circulatory Support for Shock in the Critical Care Cardiology Trials Network (CCCTN) Registry.在重症心脏病学试验网络（CCCTN）注册中心，临时机械循环支持在休克中的临床实践模式。
Circ Heart Fail. 2019 Nov;12(11):e006635. doi: 10.1161/CIRCHEARTFAILURE.119.006635. Epub 2019 Nov 11.
6
Shock Team Approach in Refractory Cardiogenic Shock Requiring Short-Term Mechanical Circulatory Support: A Proof of Concept.针对需要短期机械循环支持的顽固性心源性休克的休克团队治疗方法：概念验证
Circulation. 2019 Jul 2;140(1):98-100. doi: 10.1161/CIRCULATIONAHA.119.040654. Epub 2019 Jul 1.
7
Cardiogenic Shock Classification to Predict Mortality in the Cardiac Intensive Care Unit.心原性休克分类预测心脏重症监护病房死亡率。
J Am Coll Cardiol. 2019 Oct 29;74(17):2117-2128. doi: 10.1016/j.jacc.2019.07.077. Epub 2019 Sep 20.
8
Rationale and design of DanGer shock: Danish-German cardiogenic shock trial.背景和设计：丹麦-德国心原性休克试验（DanGer 休克试验）。
Am Heart J. 2019 Aug;214:60-68. doi: 10.1016/j.ahj.2019.04.019. Epub 2019 May 6.
9
Improved Outcomes Associated with the use of Shock Protocols: Updates from the National Cardiogenic Shock Initiative.休克方案的应用与改善预后相关：国家心源性休克倡议的最新进展。
Catheter Cardiovasc Interv. 2019 Jun 1;93(7):1173-1183. doi: 10.1002/ccd.28307. Epub 2019 Apr 25.
10
Standardized Team-Based Care for Cardiogenic Shock.标准化的以团队为基础的心源性休克治疗方案。
J Am Coll Cardiol. 2019 Apr 9;73(13):1659-1669. doi: 10.1016/j.jacc.2018.12.084.