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儿童鞘内注射碘帕醇:临床及诊断结果

Intrathecal administration of iopamidol in children: clinical and diagnostic results.

作者信息

Wells R G, Seidel F G, Sty J R, Swick H M

机构信息

Department of Radiology, Children's Hospital of Wisconsin, Milwaukee.

出版信息

Pediatr Radiol. 1988;18(3):190-3. doi: 10.1007/BF02390393.

Abstract

An open label, noncomparative clinical trial of intrathecal iopamidol in children was performed. Sixty-one subjects between the ages of 24 days and 17 years were studied. Opacification of the subarachnoid space was adequate in all cases. Mild adverse reactions were detected in 10% of the participants. Seizures, EEG alterations or other severe reactions did not occur. The findings confirm the efficacy and safety of iopamidol as an intrathecal contrast medium in pediatrics.

摘要

开展了一项关于鞘内注射碘帕醇用于儿童的开放性、非对照临床试验。研究了61名年龄在24天至17岁之间的受试者。所有病例蛛网膜下腔均显影良好。10%的参与者检测到轻度不良反应。未发生癫痫、脑电图改变或其他严重反应。这些发现证实了碘帕醇作为儿科鞘内造影剂的有效性和安全性。

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