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使用健康效用指数第二代和第三代衡量人工耳蜗植入对老年人健康相关生活质量的影响。

The impact of cochlear implantation on health-related quality of life in older adults, measured with the Health Utilities Index Mark 2 and Mark 3.

作者信息

Andries Ellen, Gilles Annick, Topsakal Vedat, Vanderveken Olivier, Van de Heyning Paul, Van Rompaey Vincent, Mertens Griet

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital (UZA), Antwerp, Belgium.

Experimental Laboratory of Translational Neurosciences and Dento-Otolaryngology, Faculty of Medicine and Health Sciences, University of Antwerp (UA), Antwerp, Belgium.

出版信息

Eur Arch Otorhinolaryngol. 2022 Feb;279(2):739-750. doi: 10.1007/s00405-021-06727-3. Epub 2021 Mar 8.

DOI:10.1007/s00405-021-06727-3
PMID:33683447
Abstract

PURPOSE

To determine the usefulness of the Health Utilities Index (HUI) in older cochlear implant (CI) recipients, the primary aims were: (1) to assess health-related quality of life (HRQoL), measured with HUI, in older CI candidates while comparing with age- and gender-matched normal-hearing controls; (2) to compare HRQoL after CI with the pre-operative situation, using HUI and the Nijmegen cochlear implant questionnaire (NCIQ). The difference between pre- and postoperative speech intelligibility in noise (SPIN) and in quiet (SPIQ) and the influence of pre-operative vestibular function on HRQoL in CI users were also studied.

METHODS

Twenty CI users aged 55 years and older with bilateral severe-to-profound postlingual sensorineural hearing loss and an age- and gender-matched normal-hearing control group were included. HRQoL was assessed with HUI Mark 2 (HUI2), HUI Mark 3 (HUI3) and NCIQ. The CI recipients were evaluated pre-operatively and 12 months postoperatively.

RESULTS

HUI3 Hearing (p = 0.02), SPIQ (p < 0.001), SPIN (p < 0.001) and NCIQ (p = 0.001) scores improved significantly comparing pre- and postoperative measurements in the CI group. No significant improvement was found comparing pre- and postoperative HUI3 Multi-Attribute scores (p = 0.07). The HUI3 Multi-Attribute score after CI remained significantly worse (p < 0.001) than those of the control group. Vestibular loss was significantly related to a decrease in HUI3 Multi-Attribute (p = 0.037) and HUI3 Emotion (p = 0.021) scores.

CONCLUSION

The HUI is suitable to detect differences between normal-hearing controls and CI users, but might underestimate HRQoL changes after CI in CI users over 55.

摘要

目的

为确定健康效用指数(HUI)在老年人工耳蜗(CI)接受者中的效用,主要目的如下:(1)在与年龄和性别匹配的正常听力对照组进行比较时,使用HUI评估老年CI候选者的健康相关生活质量(HRQoL);(2)使用HUI和奈梅亨人工耳蜗问卷(NCIQ),比较CI术后与术前的HRQoL情况。还研究了CI使用者术前和术后在噪声环境下(SPIN)和安静环境下(SPIQ)言语清晰度的差异以及术前前庭功能对HRQoL的影响。

方法

纳入20名年龄在55岁及以上、患有双侧重度至极重度语后感音神经性听力损失的CI使用者以及一个年龄和性别匹配的正常听力对照组。使用HUI Mark 2(HUI2)、HUI Mark 3(HUI3)和NCIQ评估HRQoL。对CI接受者在术前和术后12个月进行评估。

结果

与CI组术前和术后测量结果相比,HUI3听力(p = 0.02)、SPIQ(p < 0.001)、SPIN(p < 0.001)和NCIQ(p = 0.001)得分有显著改善。术前和术后HUI3多属性得分比较未发现显著改善(p = 0.07)。CI术后的HUI3多属性得分仍显著低于对照组(p < 0.001)。前庭功能丧失与HUI3多属性得分(p = 0.037)和HUI3情绪得分(p = 0.

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