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上皮内自身免疫性大疱性皮肤病的疾病活动评估和治疗。

Intraepithelial autoimmune bullous dermatoses disease activity assessment and therapy.

机构信息

Department of Dermatology, Mayo Clinic, Rochester, Minnesota.

Department of Dermatology, Mayo Clinic, Rochester, Minnesota; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

出版信息

J Am Acad Dermatol. 2021 Jun;84(6):1523-1537. doi: 10.1016/j.jaad.2021.02.073. Epub 2021 Mar 5.

Abstract

Intraepithelial autoimmune blistering dermatoses are a rare group of skin disorders characterized by disruptions of inter-keratinocyte connections within the epidermis through the action of autoantibodies. The second article in this continuing medical education series presents validated disease activity scoring systems, serologic parameters of disease, treatments, and clinical trials for pemphigus and its subtypes.

摘要

上皮内自身免疫性水疱性皮肤病是一组罕见的皮肤疾病,其特征是自身抗体作用于表皮内的角质形成细胞间连接,导致其破坏。这个继续医学教育系列的第二篇文章介绍了天疱疮及其亚型的经验证的疾病活动评分系统、疾病的血清学参数、治疗方法和临床试验。

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