Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Epiphany Dermatology, Dallas, Texas.
J Am Acad Dermatol. 2021 Jun;84(6):1507-1519. doi: 10.1016/j.jaad.2020.11.075. Epub 2021 Mar 5.
Intraepithelial autoimmune blistering dermatoses are a rare group of skin disorders characterized by the intraepithelial disruption of intercellular connections through the action of autoantibodies. The first article in this continuing medical education series explores the background, epidemiology, clinical features, and diagnostic criteria of each of the major intraepithelial autoimmune blistering dermatoses, including pemphigus foliaceus, pemphigus erythematosus, pemphigus herpetiformis, fogo selvagem, pemphigus vulgaris, pemphigus vegetans, drug-induced pemphigus, IgA pemphigus, IgG/IgA pemphigus, and paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome.
上皮内自身免疫性水疱性皮肤病是一组罕见的皮肤疾病，其特征为通过自身抗体的作用导致细胞间连接的上皮内破坏。本继续教育系列的第一篇文章探讨了每种主要的上皮内自身免疫性水疱性皮肤病（包括落叶型天疱疮、红斑型天疱疮、疱疹样天疱疮、野火症、寻常型天疱疮、增殖型天疱疮、药物诱导性天疱疮、IgA 天疱疮、IgG/IgA 天疱疮和副肿瘤性天疱疮/副肿瘤性自身免疫性多器官综合征）的背景、流行病学、临床特征和诊断标准。
