黏膜下自身免疫性大疱性皮肤病的疾病活动评估与治疗。
Subepithelial autoimmune bullous dermatoses disease activity assessment and therapy.
机构信息
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Department of Dermatology, Mayo Clinic, Rochester, Minnesota; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
出版信息
J Am Acad Dermatol. 2021 Jul;85(1):18-27. doi: 10.1016/j.jaad.2020.05.161. Epub 2021 Mar 5.
Subepidermal (subepithelial) autoimmune blistering dermatoses are a group of rare skin disorders characterized by the disruption of the dermal-epidermal junction through the action of autoantibodies. The fourth article in this continuing medical education series presents the current validated disease activity scoring systems, serologic parameters, treatments, and clinical trials for bullous pemphigoid, mucous membrane pemphigoid, epidermolysis bullosa acquisita, bullous systemic lupus erythematosus, anti-p200 pemphigoid, linear IgA bullous dermatosis, and dermatitis herpetiformis.
表皮下（上皮下）自身免疫性水疱性皮肤病是一组罕见的皮肤疾病，其特征是自身抗体作用导致真皮-表皮连接中断。本继续教育系列的第四篇文章介绍了大疱性类天疱疮、黏膜类天疱疮、获得性大疱性表皮松解症、大疱性系统性红斑狼疮、抗 p200 天疱疮、线状 IgA 大疱性皮病和疱疹样皮炎的当前验证疾病活动评分系统、血清学参数、治疗方法和临床试验。
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