Universidade Estadual Paulista (UNESP), Faculdade de Medicina, Departamento de Especialidades Cirúrgicas e Anestesiologia, Botucatu, SP, Brazil.
Universidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia e Anestesiologia Veterinária, Botucatu, SP, Brazil.
Braz J Anesthesiol. 2021 Sep-Oct;71(5):517-522. doi: 10.1016/j.bjane.2021.02.007. Epub 2021 Feb 3.
Inhaled anesthetics are used worldwide for anesthesia maintenance both in human and veterinary operating rooms. High concentrations of waste anesthetic gases can lead to health risks for the professionals exposed. Considering that anesthetic pollution in a veterinary surgical center in developing countries is unknown, this study aimed, for the first time, to measure the residual concentration of isoflurane in the air of operating rooms for small animals in a Brazilian university hospital.
Residual isoflurane concentrations were measured by an infrared analyzer at the following sites: corner opposite to anesthesia machine; breathing zones of the surgeon, anesthesiologist, and patient (animal); and in front of the anesthesia machine at three time points, that is, 5, 30 and 120 minutes after anesthesia induction.
Mean residual isoflurane concentrations gradually increased in the corner opposite to anesthesia machine and in the breathing zones of the surgeon and the anesthesiologist (p < 0.05). There was an increase at 30 minutes and 120 minutes when compared to the initial time points in the animal's breathing zone, and in the front of the anesthesia machine (p < 0.05). There was no significant difference at measurement sites regardless of the moment of assessment.
This study reported high residual isoflurane concentrations in veterinary operating rooms without an exhaust system, which exceeds the limit recommended by an international agency. Based on our findings, there is urgent need to implement exhaust systems to reduce anesthetic pollution and decrease occupational exposure.
吸入麻醉剂在全球范围内被用于人类和兽医手术室的麻醉维持。高浓度的废气麻醉剂会对暴露在其中的专业人员的健康造成风险。考虑到发展中国家兽医手术中心的麻醉污染情况未知，本研究首次旨在测量巴西一所大学医院小动物手术室空气中异氟烷的残留浓度。
通过红外分析仪在以下位置测量残留异氟烷浓度：麻醉机对面的角落；外科医生、麻醉师和患者（动物）的呼吸区；以及麻醉机前三个时间点，即麻醉诱导后 5、30 和 120 分钟。
麻醉机对面的角落以及外科医生和麻醉师的呼吸区的异氟烷残留浓度逐渐增加（p < 0.05）。与初始时间点相比，动物呼吸区和麻醉机前的异氟烷浓度在 30 分钟和 120 分钟时均有所增加（p < 0.05）。无论评估时刻如何，测量点均无显著差异。
本研究报告了无排气系统的兽医手术室中残留异氟烷浓度较高，超过了国际机构推荐的限值。根据我们的发现，迫切需要实施排气系统以减少麻醉污染和降低职业暴露。
