Rebiai Abdelkrim, Hemmami Hadia, Zeghoud Soumeia, Ben Seghir Bachir, Kouadri Imane, Eddine Laouini Salah, Elboughdiri Noureddine, Ghareba Saad, Ghernaout Djamel, Abbas Nadir
Laboratory Valorisation and Technology of Saharan Resources (VTRS), University of El-Oued, P.O. Box 789, El- Oued 39000, Algeria.
Laboratory of Industrial Analysis and Materials Engineering (LAGIM), University 8 May 1945, P.O. Box 401, Guelma 24000, Algeria.
Comb Chem High Throughput Screen. 2022;25(6):945-972. doi: 10.2174/1386207324666210309102239.
The efficiency of herbal medicinal products depends on the quantity of active ingredients in them, which can vary considerably in different contents. Hence, the quality control of herbal medicines is a critical concern.
This paper aims to provide a succinct review of recent chemometrics applications in solving the uncertainty of the authentication of herbal medicines over the last two decades.
Studies involving chemometrics applications in conjunction with various analytical methods have been categorized according to the type of research used in the quality evaluation of different samples, including chromatographic (HPLC, GC-MS) and spectroscopic analysis (UVVis, FTIR, NMR, and MS).
This review consists of over 90 studies illustrating the relevance of chemometrics methods in the discrimination based on the key bioactive components and phytochemical diversity of several herbs from closely related species. In addition to the prediction of the active components, the distinction between varieties and hybrids was accomplished through quantitative analysis techniques.
Methods of chemometrics have provided an important and potent tool for the quality control and authentication of various herbs.
草药产品的功效取决于其中活性成分的含量，而不同批次的含量可能差异很大。因此，草药的质量控制是一个至关重要的问题。
本文旨在简要回顾近二十年来化学计量学在解决草药鉴定不确定性方面的应用。
根据用于不同样品质量评估的研究类型，对涉及化学计量学与各种分析方法结合应用的研究进行了分类，包括色谱分析（HPLC、GC-MS）和光谱分析（UV-Vis、FTIR、NMR和MS）。
本综述涵盖了90多项研究，阐明了化学计量学方法在基于几种近缘物种草药的关键生物活性成分和植物化学多样性进行鉴别方面的相关性。除了预测活性成分外，还通过定量分析技术实现了品种和杂种之间的区分。
化学计量学方法为各种草药的质量控制和鉴定提供了重要且有效的工具。
