Respiratory Care Department, King Saud Abdul-Aziz University for Health Science, Riyadh, Saudi Arabia.
University of Ala bama at Birmingham, Birmingham, Ala bama.
Respir Care. 2021 Jun;66(6):936-942. doi: 10.4187/respcare.08559. Epub 2021 Mar 9.
There is a paucity of research on e-cigarette use among adults with chronic lung disease. Accordingly, little is known about the factors that may contribute to e-cigarette use in this population. The purpose of this study was to evaluate the relationship between chronic lung disease and e-cigarette use and to determine whether binge drinking moderates this relationship.
Data were derived from the 2018 Behavioral Risk Factor Surveillance System (BRFSS). Logistic regression was used to test the association between chronic lung disease status and e-cigarette use, controlling for demographic variables and chronic health conditions. We conducted moderation analyses to test the hypothesis that the association between chronic lung disease and lifetime e-cigarette use would be modified by binge drinking.
The prevalence of lifetime e-cigarette use was higher among adults with chronic lung disease than among those without, and more frequent binge drinking was associated with an increased likelihood of lifetime e-cigarette use independent of chronic lung disease status. Binge drinking moderated the relationship between chronic lung disease and lifetime use of e-cigarettes such that the association between chronic lung disease and e-cigarette use was weaker among those who engaged in more episodes of binge drinking in the past 30 d. Among those without chronic lung disease, binge drinking was associated with an increased likelihood of e-cigarette use.
E-cigarette use appears to be more common among adults with chronic lung disease. Although binge drinking was positively associated with e-cigarette use, more frequent binge drinking weakened the relationship between chronic lung disease and e-cigarette use. Though future studies are needed to determine precisely how binge drinking affects this association, it is possible that individuals with chronic lung disease who binge drink more frequently use e-cigarettes less frequently, despite an increased likelihood of having ever used an e-cigarette. (ClinicalTrials.gov registration NCT04135404.).
目前针对慢性肺病患者使用电子烟的研究较少。因此，对于可能导致这一人群使用电子烟的因素知之甚少。本研究旨在评估慢性肺病与电子烟使用之间的关系，并确定 binge drinking 是否会调节这种关系。
数据来自 2018 年行为风险因素监测系统（BRFSS）。使用逻辑回归检验慢性肺病状态与电子烟使用之间的关联，同时控制人口统计学变量和慢性健康状况。我们进行了调节分析，以检验慢性肺病与终生电子烟使用之间的关联是否会因 binge drinking 而改变的假设。
与没有慢性肺病的成年人相比，患有慢性肺病的成年人更有可能使用过电子烟，并且更频繁的 binge drinking 与终生使用电子烟的可能性增加有关，而与慢性肺病状态无关。 binge drinking 调节了慢性肺病与终生使用电子烟之间的关系，使得在过去 30 天内 binge drinking 次数较多的人群中，慢性肺病与电子烟使用之间的关联较弱。在没有慢性肺病的成年人中，binge drinking 与使用电子烟的可能性增加有关。
电子烟的使用在患有慢性肺病的成年人中似乎更为普遍。尽管 binge drinking 与电子烟使用呈正相关，但 binge drinking 越频繁，慢性肺病与电子烟使用之间的关系就越弱。尽管需要进一步的研究来确定 binge drinking 如何影响这种关联，但患有慢性肺病且 binge drinking 更频繁的个体可能会更频繁地使用电子烟，尽管他们更有可能曾经使用过电子烟。（ClinicalTrials.gov 注册号 NCT04135404）。
