Raghu Prashanth, Jeevanandham Balaji, Ramachandran Rajoo, Ralph Jeffrey, Paneerselvam Pranesh
Department of Radiology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, Tamil Nadu, India.
Ann Indian Acad Neurol. 2020 Nov-Dec;23(6):811-813. doi: 10.4103/aian.AIAN_462_19. Epub 2020 Dec 18.
Epilepsy is a common neurological condition with varied etiological causes, with temporal lobe epilepsy being the most common. Among the varied etiologies of temporal lobe epilepsy, mesial temporal sclerosis is an important one and it presents as intractable epilepsy. However, we describe here a case of intractable temporal lobe epilepsy with a rather rare etiology, calcifying pseudo neoplasm of neuraxis (CAPNON) syndrome. CAPNON is a rare benign lesion that can occur anywhere in the central nervous system. The thought process till date is to excise any intracranial space occupying lesion to relieve pressure and for a better prognosis, which is not questionable. However, we feel in case of CAPNON, wait and watch protocol can be used to a better effect with radiological and clinical follow-up. Above all surgical excision was primarily done due to imaging confusion over CAPNON and this article comes up with few key findings to clinch the radiological diagnosis of CAPNON.
癫痫是一种常见的神经系统疾病，病因多样，其中颞叶癫痫最为常见。在颞叶癫痫的各种病因中，内侧颞叶硬化是一个重要原因，它表现为难治性癫痫。然而，我们在此描述一例病因相当罕见的难治性颞叶癫痫病例，即神经轴钙化性假瘤（CAPNON）综合征。CAPNON是一种罕见的良性病变，可发生于中枢神经系统的任何部位。迄今为止的思路是切除任何颅内占位性病变以减轻压力并获得更好的预后，这一点无可置疑。然而，我们认为对于CAPNON病例，采用观察等待方案并进行影像学和临床随访可能会取得更好的效果。最重要的是，由于对CAPNON的影像学诊断存在混淆，最初进行了手术切除，本文提出了一些关键发现以明确CAPNON的影像学诊断。
