Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Guangzhou, Guangdong Province, China.
Psychooncology. 2021 Jun;30(6):901-909. doi: 10.1002/pon.5668. Epub 2021 Mar 10.
Be Resilient to Breast Cancer (BRBC), a theoretically-derived, resilience-based, culturally-tailored, supportive-expressive group therapy (SEGT), has been developed to help promote patients' resilience in breast cancer. Data from patients receiving BRBC intervention was utilized to explore and define characteristics of resilience patterns and their transitions over time.
Resilience was used as a primary outcome and 391 patients completed Resilience Scale Specific to Cancer at enrollment (T0), 2 months (T1), 6 months(T2), and 12 months (T3) after intervention. latent profile transition analysis was performed to model the change in resilience and predict positive transitioning probabilities between resilience patterns (from one pattern to another pattern with a higher level) over time.
One hundred and forty four resilience patterns were identified after BRBC intervention. 33.1%, 50.3%, and 40.5% of patients experienced positive resilience transitions from T0 to T1, T1 to T2, and T2 to T3, respectively. Patients with middle age, unmarried status, higher education level, and less advanced tumor stage were more likely to experience positive resilience transitions.
Different transitions of resilience patterns are observed after BRBC intervention. Age, marital status, education, and tumor stage may be four factors affecting the efficacy of SEGT intervention in breast cancer.
乳腺癌韧性计划(BRBC)是一种基于理论、韧性、文化适应性和支持表达的小组治疗方法,旨在帮助促进乳腺癌患者的韧性。利用接受 BRBC 干预的患者数据,探索和定义韧性模式的特征及其随时间的变化。
将韧性作为主要结局指标,391 名患者在干预前(T0)、2 个月(T1)、6 个月(T2)和 12 个月(T3)时完成了特定于癌症的韧性量表。采用潜在剖面转移分析来模拟韧性的变化,并预测韧性模式之间(从一种模式转变为另一种更高水平的模式)在不同时间点的积极转变概率。
BRBC 干预后确定了 144 种韧性模式。分别有 33.1%、50.3%和 40.5%的患者在 T0 到 T1、T1 到 T2 和 T2 到 T3 时经历了积极的韧性转变。年龄在中年、未婚、教育程度较高和肿瘤分期较低的患者更有可能经历积极的韧性转变。
BRBC 干预后观察到不同的韧性模式转变。年龄、婚姻状况、教育程度和肿瘤分期可能是影响乳腺癌 SEGT 干预效果的四个因素。