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与疫情反弹州的成年人相比,青少年和青年中的 COVID-19 患病率。

Prevalence of COVID-19 in adolescents and youth compared with older adults in states experiencing surges.

机构信息

Department of Pediatrics, New York Medical College, Valhalla, New York, United States of America.

Department of Psychology, Touro College & University System, New York, New York, United States of America.

出版信息

PLoS One. 2021 Mar 10;16(3):e0242587. doi: 10.1371/journal.pone.0242587. eCollection 2021.

Abstract

PURPOSE

There has been considerable controversy regarding susceptibility of adolescents (10-19 years) and youth (15-24 years) to COVID-19. However, a number of studies have reported that adolescents are significantly less susceptible than older adults. Summer 2020 provided an opportunity to examine data on prevalence since after months of lockdowns, with the easing of restrictions, people were mingling, leading to surges in cases.

METHODS

We examined data from Departments of Health websites in six U.S. states experiencing surges in cases to determine prevalence of COVID-19, and two prevalence-related measures, in adolescents and youth as compared to older adults. The two other measures related to prevalence were: (Percentage of cases observed in a given age group) ÷ (percentage of cases expected based on population demographics); and percentage deviation, or [(% observed-% expected)/ % expected] x 100.

RESULTS

Prevalence of COVID-19 for adolescents and for youth was significantly greater than for older adults (p < .00001), as was percentage observed ÷ percentage expected (p < .005). The percentage deviation was significantly greater in adolescents/youth than in older adults (p < 0.00001) when there was an excess of observed cases over what was expected, and significantly less when observed cases were fewer than expected (p< 0.00001).

CONCLUSIONS

Our results are contrary to previous findings that adolescents are less susceptible than older adults. Possible reasons for the findings are suggested, and we note that public health messaging targeting adolescents and youth might be helpful in curbing the pandemic. Also, the findings of the potential for high transmission among adolescents and youth, should be factored into decisions regarding school reopening.

摘要

目的

关于青少年(10-19 岁)和青年(15-24 岁)对 COVID-19 的易感性存在相当大的争议。然而,许多研究报告称,青少年的易感性明显低于老年人。2020 年夏天提供了一个机会,可以检查自几个月的封锁以来发病率的数据,随着限制的放宽,人们开始交往,导致病例激增。

方法

我们检查了美国六个州卫生部门网站的数据,以确定青少年和青年以及老年人中 COVID-19 的发病率,以及与发病率相关的两个指标。另外两个与发病率相关的指标是:(观察到的特定年龄组的病例数)÷(基于人口统计的预期病例数);以及百分比偏差,或[(观察到的百分比-预期百分比)/预期百分比] x 100。

结果

青少年和青年的 COVID-19 发病率明显高于老年人(p <.00001),观察到的百分比÷预期百分比也明显更高(p <.005)。当观察到的病例数超过预期时,青少年/青年的百分比偏差明显大于老年人(p < 0.00001),而当观察到的病例数少于预期时,百分比偏差明显小于老年人(p < 0.00001)。

结论

我们的结果与之前的发现相反,即青少年的易感性低于老年人。对这些发现提出了可能的原因,并指出针对青少年和青年的公共卫生信息传递可能有助于遏制大流行。此外,在决定学校重新开放时,应考虑到青少年和青年之间存在高传播的可能性。

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