Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.
Int J Sports Med. 2021 Oct;42(11):1035-1042. doi: 10.1055/a-1380-4219. Epub 2021 Mar 9.
Our study aimed to (i) utilize novel electrical cardiometry and observe acute changes in cardiac biomarkers among 24-h and 48-h ultra-marathoners, and (ii) examine whether alterations in cardiac responses were associated with the average running speed of these participants. Twenty-four 24-h and sixteen 48-h ultra-marathoners were recruited. Electrical cardiometry in the 2 groups showed significant post-race drops in systolic pressure (24-h: p=0.001; 48-h: p=0.016) and rapid increases in heart rate (24-h, p=0.004; 48-h, p=0.001). Cardiac output increased in 48-h runners (p=0.012) and stroke volume decreased in 24-h runners (p=0.009) at post-test. Six of 20 (30%) 24-h and 4 of 16 (25%) 48-h runners had high-sensitivity troponin T values above the reference interval after the races. N-terminal proB-type natriuretic peptide levels showed a 15-fold increase in 24-h runners and a 10-fold increase in 48-h runners at post-race. There was a positive correlation between delta N-terminal proB-type natriuretic peptide and running mileage (0.629, p=0.003) in 24-h ultra-marathoners. In conclusion, stroke volume and cardiac output showed inconsistent changes between the 2 groups. Average running speed has a significant effect on post-exercise elevation in cardiac biomarkers.
（i）利用新型心电描记术观察 24 小时和 48 小时超级马拉松运动员的心脏生物标志物的急性变化，（ii）检查心脏反应的变化是否与这些参与者的平均跑步速度有关。招募了 24 名 24 小时和 16 名 48 小时超级马拉松运动员。两组的电心描记术显示收缩压在赛后明显下降（24 小时：p=0.001；48 小时：p=0.016），心率迅速增加（24 小时：p=0.004；48 小时：p=0.001）。48 小时组的心输出量增加（p=0.012），24 小时组的每搏量减少（p=0.009）。赛后，20 名 24 小时跑者中有 6 名（30%）和 16 名 48 小时跑者中有 4 名（25%）的高敏肌钙蛋白 T 值高于参考区间。24 小时跑者的 N 末端 proB 型利钠肽水平在赛后增加了 15 倍，48 小时跑者增加了 10 倍。24 小时超级马拉松运动员的 delta N 末端 proB 型利钠肽与跑步里程呈正相关（0.629，p=0.003）。总之，两组之间的每搏量和心输出量显示出不一致的变化。平均跑步速度对运动后心脏生物标志物的升高有显著影响。
