Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, 423 Guardian Drive, PA, 19104, USA.
Pac Symp Biocomput. 2021;26:67-78.
Electronic Health Records (EHR) contain detailed information about a patient's medical history and can be helpful in understanding clinical outcomes among populations generally underrepresented in research, including pregnant individuals. A cesarean delivery is a clinical outcome often considered in studies as an adverse pregnancy outcome, when in reality there are circumstances in which a cesarean delivery is considered the safest or best choice given the patient's medical history, situation, and comfort. Rather than consider all cesarean deliveries to be negative outcomes, it is important to examine other risk factors that may contribute to a cesarean delivery being an adverse event. Looking at emergency admissions can be a useful way to ascertain whether or not a cesarean delivery is part of an adverse event. This study utilizes EHR data from Penn Medicine to assess patient characteristics and pregnancy-related conditions as risk factors for an emergency admission at the time of delivery. After adjusting for pregnancy number and cesarean number for each patient, preterm birth increased risk of an emergency admission, and patients younger than 25, or identifying as Black/African American, Asian, or Other/Mixed, had an increased risk. Later pregnancies and repeat cesareans decreased the risk of an emergency delivery, and White, Hispanic, and Native Hawaiian/Pacific Islander patients were at decreased risk. The same risk factors and trends were found among cesarean deliveries, except that Asian patients did not have an increased risk, and Native Hawaiian/Pacific Islander patients did not have a reduced risk in this group.
电子健康记录 (EHR) 包含患者病史的详细信息,对于了解一般研究中代表性不足的人群(包括孕妇)的临床结局非常有帮助。剖宫产是研究中常被视为不良妊娠结局的临床结局,但实际上,在某些情况下,鉴于患者的病史、情况和舒适度,剖宫产被认为是最安全或最佳的选择。不应将所有剖宫产都视为负面结果,重要的是要检查可能导致剖宫产成为不良事件的其他风险因素。查看急诊入院情况是确定剖宫产是否为不良事件的一种有用方法。本研究利用宾夕法尼亚大学医学中心的电子健康记录数据,评估患者特征和与妊娠相关的情况作为分娩时急诊入院的风险因素。在为每位患者调整了妊娠次数和剖宫产次数后,早产增加了急诊入院的风险,而年龄小于 25 岁或认定为黑人/非裔美国人、亚裔或其他/混合族裔的患者则有更高的风险。较晚的妊娠和重复剖宫产降低了急诊分娩的风险,而白人、西班牙裔和夏威夷原住民/太平洋岛民患者的风险则降低。剖宫产也存在相同的风险因素和趋势,但亚裔患者在这一组中没有增加风险,而夏威夷原住民/太平洋岛民患者没有降低风险。