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本文引用的文献

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[Meta-analysis of asthma prevalence of children aged 0-14 in surveillance cities of China].[中国监测城市0-14岁儿童哮喘患病率的Meta分析]
Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Aug 6;54(8):875-883. doi: 10.3760/cma.j.cn112150-20191015-00788.
2
[Application of pulmonary function and fractional exhaled nitric oxide tests in the standardized management of bronchial asthma in children].[肺功能与呼出一氧化氮分数检测在儿童支气管哮喘规范化管理中的应用]
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):419-424. doi: 10.7499/j.issn.1008-8830.2017.04.012.
3
Japanese guidelines for childhood asthma 2017.《2017年日本儿童哮喘指南》
Allergol Int. 2017 Apr;66(2):190-204. doi: 10.1016/j.alit.2016.11.003. Epub 2017 Jan 18.
4
Asthma control assessment in a pediatric population: comparison between GINA/NAEPP guidelines, Childhood Asthma Control Test (C-ACT), and physician's rating.儿童哮喘控制评估:GINA/NAEPP 指南、儿童哮喘控制测试(C-ACT)和医生评分的比较。
Allergy. 2014 Jun;69(6):784-90. doi: 10.1111/all.12402. Epub 2014 Apr 12.
5
Bronchodilator response as a hallmark of uncontrolled asthma: a randomised clinical trial.支气管扩张剂反应作为未控制哮喘的标志:一项随机临床试验。
J Asthma. 2014 May;51(4):405-10. doi: 10.3109/02770903.2013.878845. Epub 2014 Jan 24.
6
Clinical, economic, and humanistic burden of asthma in Canada: a systematic review.加拿大哮喘的临床、经济和人文负担:系统评价。
BMC Pulm Med. 2013 Dec 5;13:70. doi: 10.1186/1471-2466-13-70.
7
International consensus on (ICON) pediatric asthma.国际儿童哮喘共识 (ICON)。
Allergy. 2012 Aug;67(8):976-97. doi: 10.1111/j.1398-9995.2012.02865.x. Epub 2012 Jun 15.
8
The relationship of the bronchodilator response phenotype to poor asthma control in children with normal spirometry.正常肺功能儿童中支气管扩张剂反应表型与哮喘控制不佳的关系。
J Pediatr. 2011 Jun;158(6):953-959.e1. doi: 10.1016/j.jpeds.2010.11.029. Epub 2011 Jan 13.
9
The Childhood Asthma Control Test: retrospective determination and clinical validation of a cut point to identify children with very poorly controlled asthma.儿童哮喘控制测试:回顾性确定和临床验证一个切点,以识别哮喘控制非常差的儿童。
J Allergy Clin Immunol. 2010 Aug;126(2):267-73, 273.e1. doi: 10.1016/j.jaci.2010.05.031. Epub 2010 Jul 10.
10
Asthma Control Test correlates well with the treatment decisions made by asthma specialists.哮喘控制测试与哮喘专科医生做出的治疗决策具有良好的相关性。
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[支气管舒张试验与哮喘患儿哮喘控制水平的相关性]

[Correlation between bronchial dilation test and asthma control level in children with asthma].

作者信息

Liu Xin, Feng Yong, Shang Yun-Xiao

机构信息

Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang 110004, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2021 Mar;23(3):265-270. doi: 10.7499/j.issn.1008-8830.2012029.

DOI:10.7499/j.issn.1008-8830.2012029
PMID:33691920
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7969182/
Abstract

OBJECTIVE

To study the correlation between the bronchial dilation test (BDT) and asthma control level in children with asthma.

METHODS

A total of 153 children with asthma, aged 5-14 years, who attended the outpatient service from March 2016 to March 2018 were enrolled. According to the presence or absence of atopic constitution, they were divided into an allergic group with 79 children and a non-allergic group with 74 children. The correlation between BDT and Childhood Asthma Control Test (C-ACT) scores was analyzed for both groups.

RESULTS

All basic pulmonary function parameters were positively correlated with C-ACT scores in the non-allergic group ( < 0.05). Except the forced vital capacity, peak expiratory flow and maximal expiratory flow at 25% vital capacity in percent predicted values, the other pulmonary function parameters were positively correlated with C-ACT scores in the allergic group ( < 0.05). The improvement rates of all BDT parameters (except maximal expiratory flow at 25% vital capacity in the allergic group and maximal expiratory flow at 50% vital capacity in the non-allergic group) were negatively correlated with C-ACT scores in the two groups ( < 0.05).

CONCLUSIONS

The improvement rate of BDT is well correlated with C-ACT scores in children with asthma, suggesting that BDT can be used as an index for predicting asthma control level.

摘要

目的

研究支气管舒张试验(BDT)与哮喘患儿哮喘控制水平之间的相关性。

方法

选取2016年3月至2018年3月在门诊就诊的153例5 - 14岁哮喘患儿。根据是否有特应性体质,将其分为过敏组79例和非过敏组74例。分析两组中BDT与儿童哮喘控制测试(C - ACT)评分之间的相关性。

结果

非过敏组所有基本肺功能参数与C - ACT评分呈正相关(<0.05)。过敏组除用力肺活量、呼气峰值流速及25%肺活量时的最大呼气流量占预计值百分比外,其他肺功能参数与C - ACT评分呈正相关(<0.05)。两组中所有BDT参数的改善率(过敏组中25%肺活量时的最大呼气流量及非过敏组中50%肺活量时的最大呼气流量除外)与C - ACT评分呈负相关(<0.05)。

结论

BDT改善率与哮喘患儿C - ACT评分密切相关,提示BDT可作为预测哮喘控制水平的指标。