Wang Bei-Bei, Kan Qing, Zou Yun-Su, Cheng Rui, Zhou Xiao-Guang
Department of Neonatology, Children's Hospital of Nanjing Medical University, Nanjing 210008, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2021 Mar;23(3):283-287. doi: 10.7499/j.issn.1008-8830.2012020.
A healthy full-term female neonate, aged 3 days and born by vaginal delivery (with a 1-minute Apgar score of 10 and a 5-minute Apgar score of 10), had unexpected cardiac and respiratory arrests in the early morning on day 3 after birth and recovered to spontaneous breathing and heartbeat after a 10-minute resuscitation. The child had poor response and convulsion after resuscitation. Blood gas analysis showed metabolic acidosis, and amplitude-integrated EEG showed a burst-suppression pattern. She was diagnosed with sudden unexpected postnatal collapse but improved after hypothermia and symptomatic/supportive treatment. This article reports the first case of sudden unexpected postnatal collapse in China and summarizes related risk factors, pathophysiological mechanisms, and preventive and treatment measures of this disorder.
一名健康的足月女新生儿，3日龄，经阴道分娩出生（1分钟阿氏评分10分，5分钟阿氏评分10分），出生后第3天清晨意外发生心脏和呼吸骤停，经10分钟复苏后恢复自主呼吸和心跳。复苏后患儿反应差且惊厥。血气分析显示代谢性酸中毒，振幅整合脑电图显示爆发抑制模式。她被诊断为新生儿猝死综合征，但经低温治疗及对症/支持治疗后病情好转。本文报道了中国首例新生儿猝死综合征病例，并总结了该疾病的相关危险因素以及病理生理机制、预防和治疗措施。
