Heinicke H J, Hensel J
Abteilung für Nephrologie und chronische Hämodialyse, Bezirkskrankenhauses Dresden-Friedrichstadt.
Z Gesamte Inn Med. 1988 Feb 1;43(3):56-9.
Of 44 female patients with lupus erythematosus visceralis after and with manifestation of the disease, respectively, in eight women ten pregnancies developed, out of them three viable births between the 33rd and 40th week of pregnancy, one stillbirth in the 37th week of pregnancy, one miscarriage in the IIIrd month of pregnancy and five interruptions of pregnancy. It is reported on the course of the disease and pregnancy of five women, taking into particular consideration the lupus nephritis. With the help of the literature and on the basis of own experiences course of the lupus erythematosus visceralis and lupus nephritis during pregnancy, the influence of the lupus erythematosus visceralis on pregnancy and development of the child, peculiarities of the treatment of lupus erythematosus visceralis during pregnancy as well as questions of prevention and interruption of pregnancy are discussed. Finally is tried to draw universal conclusions.
在44例分别处于红斑狼疮内脏型发病期及有该疾病表现的女性患者中,8名女性共经历了10次妊娠,其中3例在妊娠第33至40周时成功分娩,1例在妊娠第37周时死产,1例在妊娠第3个月时流产,5例妊娠终止。本文报告了5名女性的疾病及妊娠过程,尤其考虑了狼疮性肾炎。借助文献并基于自身经验,讨论了妊娠期间红斑狼疮内脏型及狼疮性肾炎的病程、红斑狼疮内脏型对妊娠及胎儿发育的影响、妊娠期间红斑狼疮内脏型的治疗特点以及妊娠预防和终止的问题。最后试图得出一般性结论。