Takayama Hideo, Komura Takuya, Yoshio Takatoshi, Yanagi Masahiro, Nishino Michiko, Orita Noriaki, Nishikawa Masashi, Kagaya Takashi, Kawashima Atsuhiro, Unoura Masashi
Department of Gastroenterology, Kanazawa Medical Center.
Department of Pathology, Kanazawa Medical Center.
Nihon Shokakibyo Gakkai Zasshi. 2021;118(3):264-271. doi: 10.11405/nisshoshi.118.264.
The patient was an 81-year-old man who presented with a complaint of hoarseness. When he was 80 years old, he had developed superficial esophageal cancer and had undergone endoscopic submucosal dissection (ESD) at our hospital. Two months after the ESD, he developed hoarseness. Computed tomography (CT) scan showed no abnormal findings at that time;therefore, he was diagnosed with idiopathic vocal cord paralysis, and followed up with symptom treatment in the Gastroenterology and Otolaryngology Departments. Ten months after the ESD, a CT scan revealed mediastinal lymph node swelling. He was admitted to our hospital for histopathological examination of the lymph node using endoscopic ultrasound-fine needle aspiration (EUS-FNA). The histopathological examination revealed squamous cell carcinoma of the lymph node, similar to the primary esophageal tumor. This result suggests that laryngeal nerve paralysis involving hoarseness is caused by lymph node metastasis of superficial esophageal cancer. We report that histopathological examination with EUS-FNA helps in determining the cause of hoarseness that develops after ESD.
该患者为一名81岁男性,因声音嘶哑前来就诊。他80岁时被诊断为早期食管癌,并在我院接受了内镜黏膜下剥离术(ESD)。ESD术后两个月,他出现了声音嘶哑。当时的计算机断层扫描(CT)未发现异常;因此,他被诊断为特发性声带麻痹,并在胃肠病科和耳鼻喉科进行症状治疗随访。ESD术后十个月,CT扫描显示纵隔淋巴结肿大。他因使用超声内镜引导下细针穿刺活检(EUS-FNA)对淋巴结进行组织病理学检查而入住我院。组织病理学检查显示淋巴结鳞状细胞癌,与原发性食管肿瘤相似。这一结果表明,涉及声音嘶哑的喉返神经麻痹是由早期食管癌的淋巴结转移引起的。我们报告,EUS-FNA组织病理学检查有助于确定ESD术后出现声音嘶哑的原因。