Rai Ankit, Gajula Bhargav, Kumar Navin, Malik Akanksha
General Surgery, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Pathology, National Institute of Pathology, New Delhi, IND.
Cureus. 2021 Feb 5;13(2):e13156. doi: 10.7759/cureus.13156.
Gastrointestinal (GI) tract perforation is a surgical emergency. The epidemiology and etiology of perforation vary considerably across geography. Lower GI tract perforations in the elderly predominate in the West compared to upper GI perforations in the younger population in the tropics. Fungi and viruses have been reported to cause GI perforations in immuno-compromised individuals but it is rare in immuno-competent individuals. We report a very rare case of gastric perforation secondary to fungal gastritis in an immuno-competent 35-year-old female who presented with features of peritonitis. At emergency laparotomy, gastric perforation was found which was repaired by the Cellan-Jones method. Perforation edge biopsy findings were consistent with fungal etiology. She responded well to Antifungal therapy. We conclude that fungal etiology can be considered in patients with gastric perforation without any history of peptic ulcer disease (PUD) or use of oral non-steroidal anti-inflammatory drugs.
胃肠道穿孔是一种外科急症。穿孔的流行病学和病因在不同地区差异很大。在西方,老年人下消化道穿孔占主导,而在热带地区,年轻人以上消化道穿孔为主。据报道,真菌和病毒可导致免疫功能低下个体发生胃肠道穿孔,但在免疫功能正常的个体中很少见。我们报告了一例非常罕见的病例,一名35岁免疫功能正常的女性因真菌性胃炎继发胃穿孔,表现出腹膜炎特征。在急诊剖腹手术中,发现胃穿孔,采用Cellan-Jones方法进行修复。穿孔边缘活检结果与真菌病因一致。她对抗真菌治疗反应良好。我们得出结论,对于没有消化性溃疡病(PUD)病史或未使用口服非甾体抗炎药的胃穿孔患者,可考虑真菌病因。