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严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)在胃肠道中的表现:治疗意义

SARS-CoV-2 Virus Manifestations in the Gastrointestinal Tract: Therapeutic Implications.

作者信息

Jefremow André, Neurath Markus F

机构信息

Department of Internal Medicine 1, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Deutsches Zentrum Immuntherapie (DZI), Erlangen, Germany.

出版信息

Visc Med. 2021 Feb;37(1):63-69. doi: 10.1159/000513180. Epub 2020 Nov 24.

DOI:10.1159/000513180
PMID:33693046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7802000/
Abstract

BACKGROUND

About 1 year ago a novel virus - SARS-CoV-2 - began to spread around the world. It can lead to the disease COVID-19, which has caused more than 1 million deaths already.

SUMMARY

While it was first recognized as a disease leading to pneumonia and lung failure, we know by now that COVID-19 is more complex. COVID-19 is a systemic hyperinflammatory disease affecting not only the lungs, but also many other organs. Especially the gastrointestinal (GI) tract is often involved in COVID-19.

KEY MESSAGES

This review provides an overview of the different affected organs of the GI tract and offers information on how gastroenterologists should take care of their patients with different GI disorders.

摘要

背景

大约一年前,一种新型病毒——严重急性呼吸综合征冠状病毒2(SARS-CoV-2)——开始在全球传播。它可导致新冠肺炎疾病,该疾病已造成100多万人死亡。

总结

虽然它最初被认为是一种导致肺炎和肺衰竭的疾病,但我们现在知道新冠肺炎更为复杂。新冠肺炎是一种全身性炎症性疾病,不仅影响肺部,还影响许多其他器官。尤其是胃肠道经常受到新冠肺炎的影响。

关键信息

本综述概述了胃肠道不同的受累器官,并提供了关于胃肠病学家应如何照顾患有不同胃肠道疾病患者的信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d0e/7923939/f9e940ca98d0/vis-0037-0063-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d0e/7923939/22559f34cd45/vis-0037-0063-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d0e/7923939/f9e940ca98d0/vis-0037-0063-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d0e/7923939/22559f34cd45/vis-0037-0063-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d0e/7923939/f9e940ca98d0/vis-0037-0063-g02.jpg

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Severe Acute Respiratory Syndrome Coronavirus 2 Attachment Receptor Angiotensin-Converting Enzyme 2 Is Decreased in Crohn's Disease and Regulated By Microbial and Inflammatory Signaling.
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