Raczynski J M, Wiebe D J, Milby J B, Gurwitch R H
Division of General and Preventive Medicine, University of Alabama, Birmingham 35294.
Addict Behav. 1988;13(2):165-9. doi: 10.1016/0306-4603(88)90006-8.
Recent data reveal that only a small number of opioid addicts who attempt to detoxify from methadone maintenance programs will be successful. An irrational fear of detoxification has been postulated to be one reason for detoxification not being more efficacious. The present investigation attempted to assess both self-report and psychophysiological responses to detoxification and neutral scenes in two groups of persons on methadone maintenance. The two groups (N = 8 each) were selected by two blind interviewers as either having or not having a detoxification fear. After imagery training, subjects were asked to imagine 10 scenes, alternating between neutral and detoxification scenes with random counterbalancing for order, while the psychophysiological dependent measures and self-report anxiety and clarity ratings were assessed. Some of the self-report and psychophysiological measures were significantly different for scene type, indicating a successful manipulation of scene imagery. Further, pulse volume measures indicated greater activation in the fear group than in the non-fear group to the detoxification scenes. The results are discussed in terms of providing evidence for greater activation, presumably due to greater anxiety, for the detoxification fear subjects than the non-fear subjects specific to the detoxification imagery and in terms of potential treatment implications.
近期数据显示,只有少数尝试从美沙酮维持治疗项目中戒毒的阿片类成瘾者会成功。一种对戒毒的非理性恐惧被认为是戒毒效果不佳的一个原因。本研究试图评估两组接受美沙酮维持治疗的人员对戒毒场景和中性场景的自我报告及心理生理反应。两组(每组N = 8)由两名盲选面试官挑选,一组有戒毒恐惧,另一组没有。经过意象训练后,要求受试者想象10个场景,中性场景和戒毒场景交替出现,顺序随机平衡,同时评估心理生理相关指标以及自我报告的焦虑和清晰度评分。一些自我报告和心理生理指标因场景类型而有显著差异,表明场景意象的操控成功。此外,脉搏容积测量表明,恐惧组对戒毒场景的激活程度高于非恐惧组。本文根据戒毒恐惧受试者比非恐惧受试者在戒毒意象方面有更大激活(可能是由于更大的焦虑)的证据以及潜在的治疗意义对结果进行了讨论。