Schroeder Michael J, Kraft Casey T, Janis Jeffrey E, Kraft Monica T
From the Department of Plastic and Reconstructive Surgery, Ohio State University, Columbus, Ohio.
Private Practice, Columbus, Ohio.
Plast Reconstr Surg Glob Open. 2024 Apr 15;12(4):e5734. doi: 10.1097/GOX.0000000000005734. eCollection 2024 Apr.
Reported drug allergies are commonly encountered by surgeons and can lead to uncertainty in selecting an appropriate agent due to concerns of associated risks with related and cross-reactive drugs. This uncertainty can ultimately lead to increased infection rates.
A literature review was conducted in PubMed using a combination of the terms "allergy," "allergic reaction," "anaphylaxis," and "surgery," "surgical," or "operating room" for articles published within the last 10 years. Publications identified with these search terms were then filtered for review articles, sorted by "best match," and a maximum of 100 articles were manually reviewed for each combination of search terms.
Search results yielded 46,484 articles, 676 of which were ultimately included for manual review, based on selection criteria. Specifically, articles selected for inclusion focused on surgical allergic reactions that were either related to mechanism of action, causative agent for the allergic reaction, timing of allergic reaction, or recommendations for appropriate management.
Allergic reactions can be a common occurrence in the operative room. Knowledge of likely causative agents, timing of a reaction to various agents, and appropriate management in the immediate and delayed setting can improve outcomes and safety for plastic surgery patients.
外科医生经常遇到报告的药物过敏情况，由于担心相关和交叉反应药物的风险，这可能导致在选择合适药物时产生不确定性。这种不确定性最终可能导致感染率上升。
在PubMed上进行文献综述，使用“过敏”“过敏反应”“过敏症”以及“手术”“外科的”或“手术室”等术语的组合，搜索过去10年内发表的文章。然后，对通过这些搜索词识别出的出版物进行筛选，以获取综述文章，按“最佳匹配”排序，对每个搜索词组合最多手动审阅100篇文章。
搜索结果产生了46484篇文章，根据选择标准，最终有676篇文章被纳入人工审阅。具体而言，入选的文章重点关注与作用机制、过敏反应的致病因素、过敏反应发生时间或适当管理建议相关的手术过敏反应。
过敏反应在手术室中可能很常见。了解可能的致病因素、对各种药物的反应时间以及在即时和延迟情况下的适当管理，可以改善整形外科患者的治疗效果和安全性。
