Ballas S K, Kocher W
Cardeza Foundation for Hematologic Research, Philadelphia, PA 19107.
Am J Hematol. 1988 May;28(1):37-9. doi: 10.1002/ajh.2830280108.
We have used the new Technicon H.1 Hematology Analyzer to determine the indices of erythrocytes obtained from 18 nonthalassemic (alpha alpha/alpha alpha genotype) adult patients with Hb SC disease. Controls were 14 normal black adults and 29 white adults. The data showed that SC erythrocytes are significantly smaller than normal RBC (P less than .001) with a significantly higher MCHC value (P less than .001) than controls. These features of SC RBC could not be reproduced by an Ortho ELT-8 electronic counter. Hb SC erythrocytes have unique indices which are best demonstrated either by semimanual methods or by the H.1 system.
我们使用新型Technicon H.1血液分析仪测定了18例非地中海贫血（αα/αα基因型）成年Hb SC病患者红细胞的各项指标。对照组为14名正常黑人成年人和29名正常白人成年人。数据显示，与对照组相比，Hb SC病患者的红细胞明显更小（P<0.001），平均血红蛋白浓度（MCHC）值显著更高（P<0.001）。Ortho ELT - 8电子血细胞计数器无法重现Hb SC病患者红细胞的这些特征。Hb SC病患者的红细胞具有独特的指标，通过半手工方法或H.1系统能得到最佳呈现。
