米安色林治疗期间催乳素对色氨酸的反应。
Prolactin response to tryptophan during mianserin treatment.
作者信息
Cowen P J
机构信息
Department of Psychiatry, Oxford University, United Kingdom.
出版信息
Am J Psychiatry. 1988 Jun;145(6):740-1. doi: 10.1176/ajp.145.6.740.
PMID:3369564
Abstract
Unlike tricyclic antidepressants and monoamine oxidase inhibitors, mianserin did not increase prolactin response to the 5-hydroxytryptamine (5-HT) precursor tryptophan in nine patients with major depression. Antidepressant drugs apparently produce dissimilar effects on this aspect of brain 5-HT function in depressed patients.
摘要
与三环类抗抑郁药和单胺氧化酶抑制剂不同，米安色林在9名重度抑郁症患者中并未增强催乳素对5-羟色胺（5-HT）前体色氨酸的反应。抗抑郁药显然对抑郁症患者大脑5-HT功能的这一方面产生不同的影响。
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