Prolactin response to tryptophan during mianserin treatment.

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作者信息

Cowen P J

机构信息

Department of Psychiatry, Oxford University, United Kingdom.

出版信息

Am J Psychiatry. 1988 Jun;145(6):740-1. doi: 10.1176/ajp.145.6.740.

DOI:10.1176/ajp.145.6.740

PMID:3369564

Abstract

Unlike tricyclic antidepressants and monoamine oxidase inhibitors, mianserin did not increase prolactin response to the 5-hydroxytryptamine (5-HT) precursor tryptophan in nine patients with major depression. Antidepressant drugs apparently produce dissimilar effects on this aspect of brain 5-HT function in depressed patients.

摘要