• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

撤回：β-拉帕醌通过靶向哺乳动物雷帕霉素靶蛋白（mTOR）/PI3K/AKT 通路、活性氧（ROS）产生和自噬诱导抑制鼻咽癌的发生。

Retracted: Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction.

机构信息

Department of Oncology, Nanchang University, Nanchang, Jiangxi, China (mainland).

Department of Oncology, Jiujiang First People's Hospital, Jiujiang, Jiangxi, China (mainland).

出版信息

Med Sci Monit. 2021 Mar 11;27:e931623. doi: 10.12659/MSM.931623.

DOI:10.12659/MSM.931623
PMID:33704260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7962494/
Abstract

Approval for publication of this manuscript was not obtained by all the authors, which is in breach of this journal's editorial guidelines. Reference: Yongqing Han, Dayou Shi, Jingao Li: Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction.  Med Sci Monit 2019; 25:8995-9002. 10.12659/MSM.915463.

摘要

该手稿的发表并未获得所有作者的批准，这违反了本刊的编辑准则。参考文献：韩永清、时大勇、李敬高：β-拉帕醌通过靶向哺乳动物雷帕霉素靶蛋白（mTOR）/PI3K/AKT 通路、活性氧（ROS）产生和自噬诱导抑制鼻咽癌。医学科学监测 2019；25:8995-9002. 10.12659/MSM.915463.

相似文献

1
Retracted: Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction.撤回：β-拉帕醌通过靶向哺乳动物雷帕霉素靶蛋白（mTOR）/PI3K/AKT 通路、活性氧（ROS）产生和自噬诱导抑制鼻咽癌的发生。
Med Sci Monit. 2021 Mar 11;27:e931623. doi: 10.12659/MSM.931623.
2
Retracted: Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway.撤回：苦参碱在吉西他滨耐药的人胰腺癌细胞中的抗增殖作用是通过线粒体介导的细胞凋亡、抑制细胞迁移、侵袭抑制以及哺乳动物雷帕霉素靶蛋白（mTOR）-TOR/PI3K/AKT 信号通路来介导的。
Med Sci Monit. 2021 Mar 25;27:e932342. doi: 10.12659/MSM.932342.
3
Retracted: Withaferin-A Inhibits Growth of Drug-Resistant Breast Carcinoma by Inducing Apoptosis and Autophagy, Endogenous Reactive Oxygen Species (ROS) Production, and Inhibition of Cell Migration and Nuclear Factor kappa B (Nf-κB)/Mammalian Target of Rapamycin (m-TOR) Signalling Pathway.撤回：醉茄素 A 通过诱导细胞凋亡和自噬、内源性活性氧 (ROS) 产生、抑制细胞迁移和核因子 kappa B (NF-κB)/哺乳动物雷帕霉素靶蛋白 (mTOR) 信号通路来抑制耐药性乳腺癌的生长。
Med Sci Monit. 2021 Mar 25;27:e932348. doi: 10.12659/MSM.932348.
4
Retracted: Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells In Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway.撤回：小白菊内酯在体外和小鼠肿瘤异种移植模型中抑制MDA-T32乳头状甲状腺癌细胞增殖，并通过下调雷帕霉素哺乳动物靶蛋白（mTOR）/PI3K/AKT信号通路激活自噬和凋亡。
Med Sci Monit. 2021 Mar 11;27:e931025. doi: 10.12659/MSM.931025.
5
Retracted: Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway.撤稿：抗糖尿病药物二甲双胍对卵巢癌细胞的抗癌活性涉及抑制富含半胱氨酸的 61（Cyr61）/Akt/雷帕霉素靶蛋白（mTOR）信号通路。
Med Sci Monit. 2021 Mar 25;27:e932331. doi: 10.12659/MSM.932331.
6
Retracted: Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of Mitogen-Activated Protein Kinase (MAPK) and PI3K/AKT Signaling Pathways.撤回：二萜类化合物鞣花醇通过诱导线粒体依赖性细胞凋亡、产生内源性活性氧 (ROS)、线粒体膜电位丧失以及抑制丝裂原活化蛋白激酶 (MAPK) 和 PI3K/AKT 信号通路，选择性抑制人甲状腺癌细胞生长。
Med Sci Monit. 2021 Mar 25;27:e932341. doi: 10.12659/MSM.932341.
7
ROS Promote Ox-LDL-Induced Platelet Activation by Up-Regulating Autophagy Through the Inhibition of the PI3K/AKT/mTOR Pathway.活性氧通过抑制PI3K/AKT/mTOR通路上调自噬，促进氧化型低密度脂蛋白诱导的血小板活化。
Cell Physiol Biochem. 2018;50(5):1779-1793. doi: 10.1159/000494795. Epub 2018 Nov 1.
8
Retracted: Girinimbine Inhibits the Proliferation of Human Ovarian Cancer Cells In Vitro via the Phosphatidylinositol-3-Kinase (PI3K)/Akt and the Mammalian Target of Rapamycin (mTOR) and Wnt/β-Catenin Signaling Pathways.撤回：甘来因通过磷脂酰肌醇-3-激酶（PI3K）/Akt 和雷帕霉素靶蛋白（mTOR）及 Wnt/β-连环蛋白信号通路抑制人卵巢癌细胞的体外增殖。
Med Sci Monit. 2021 Mar 11;27:e931225. doi: 10.12659/MSM.931225.
9
[Retracted] Anticancer activity of caffeic acid n‑butyl ester against A431 skin carcinoma cell line occurs via induction of apoptosis and inhibition of the mTOR/PI3K/AKT signaling pathway.[撤回]正丁基咖啡酸酯对 A431 皮肤癌细胞系的抗癌活性是通过诱导细胞凋亡和抑制 mTOR/PI3K/AKT 信号通路实现的。
Mol Med Rep. 2021 May;23(5). doi: 10.3892/mmr.2021.12011. Epub 2021 Mar 24.
10
Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.小檗碱通过下调 PI3K/Akt/mTOR 信号通路和上调 ROS 介导的线粒体功能障碍诱导肝癌 Hep3B 细胞自噬性细胞死亡。
Arch Biochem Biophys. 2021 Jan 15;697:108688. doi: 10.1016/j.abb.2020.108688. Epub 2020 Nov 21.

本文引用的文献

1
Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction.β-拉帕醌通过靶向哺乳动物雷帕霉素靶蛋白（mTOR）/PI3K/AKT 通路、活性氧（ROS）产生和自噬诱导抑制鼻咽癌细胞。
Med Sci Monit. 2019 Nov 26;25:8995-9002. doi: 10.12659/MSM.915463.